# Program 01 Breast Cancer

> **NIH NIH P30** · DANA-FARBER CANCER INST · 2022 · $42,854

## Abstract

Breast Cancer Program
Project Summary / Abstract
The mission of the Breast Cancer Program is to reduce morbidity and mortality from breast cancer through
innovative basic and translational research and the conduct of impactful clinical trials. The Program’s members
work collaboratively to advance knowledge across the continuum of breast cancer: from prevention, screening,
and early diagnosis to treatment and survivorship. The goals are to increase cure rates and reduce morbidity
among those who ultimately succumb to the disease and those who live with the late effects of therapy.
The program has 117 members (73 primary and 44 secondary), representing all seven DF/HCC institutions
and 16 academic departments. In 2019, peer-reviewed grant funding attributed to the Program was $8.1 million
in direct costs from the NCI and $2.4 million from other sponsors. During the current funding period, primary
Program members published 936 cancer-relevant papers. Of these, 28% were inter-institutional, 22% were
intra-programmatic, and 42% were inter-programmatic collaborations between two or more DF/HCC members.
To achieve the Program’s mission, our Specific Aims are to 1) Define and address the heterogeneity in
triple-negative breast cancer; 2) Characterize the biology to improve outcomes from breast cancer
metastases to the brain; 3) Improve the efficacy of immunotherapy for breast cancer; 4) Improve
personalized local-regional therapy; and 5) Ensure that Program advances serve Massachusetts and the
nation by addressing racial disparities and access to cancer care.
These Aims align closely with the DF/HCC Strategic Plan and will be achieved through the established and
invaluable CCSG infrastructure for collaborative transdisciplinary research, Shared Resources, and a unified
clinical trials apparatus that accelerates translation of the Program’s laboratory discoveries to the clinic.

## Key facts

- **NIH application ID:** 10332547
- **Project number:** 2P30CA006516-57
- **Recipient organization:** DANA-FARBER CANCER INST
- **Principal Investigator:** Eric P. Winer
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $42,854
- **Award type:** 2
- **Project period:** 1997-03-10 → 2026-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10332547

## Citation

> US National Institutes of Health, RePORTER application 10332547, Program 01 Breast Cancer (2P30CA006516-57). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10332547. Licensed CC0.

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