# Shared Resource 05: Clinical Treatment Unit/ Clinical Trials Processing Lab (CTU/CTPL-SR)

> **NIH NIH P30** · OHIO STATE UNIVERSITY · 2022 · $179,411

## Abstract

PROJECT SUMMARY – CLINICAL TREATMENT UNIT (CTU) AND CLINICAL TRIALS PROCESSING
LABORATORY (CTPL) SHARED RESOURCE (CTU/CTPL-SR)
An important scientific mission of the OSUCCC is to conduct high quality, cutting edge clinical research for the
improved understanding and advancement in treatments of human malignancies. The CTU/CTPL-SR is
composed of two different, but intimately related units, namely the Clinical Treatment Unit (CTU) and the Clinical
Trials Processing Laboratory (CTPL). The CCSG will only support the CTPL component of the shared resource;
support of the CTU component will be entirely from OSUCCC institutional funding, as has been the case for the
last two CCSG cycles. The CTU/STPL-SR manages all clinical trial biospecimen collection and processing for
samples that are sent externally, and for most clinical trials where samples are being sent to OSUCCC
investigator laboratories or shared resources. Key services, in support of all clinical trials needing biospecimen
collection, processing and shipping for the CTU/CTPL-SR include consultation on protocol design with regard to
correlative specimens, procurement and processing of correlative specimens per protocol specifications
developing protocol in-service materials, participating in site initiation visits and protocol implementation
meetings, assisting in monitoring visits and audits and shipping specimens internal or external to OSU for
analysis. The CTU/CTPL-SR coordinates with other shared resources and departments to address the wide
array of biological specimens required for current clinical trials. The Specific Aims are to: 1) provide a stable,
reliable, and cost-effective, state-of-the art unit for conducting early phase clinical trials requiring intense
monitoring and/or complex correlative specimen collection; and, 2) provide high-quality, high-volume specimen
processing, short-term storage and distribution of biospecimens collected as correlative components of phase I,
II and III translational clinical trials. During the current grant period, the CTU/CTP-SR has supported 129
investigators (60% OSUCCC members) from all five OSUCCC research programs, and procured a total of
104,831 specimens from patients enrolled in 729 clinical trials. Also, the CTU/CTPL-SR contributed to 102
publications (36 > 10 impact factor). The CTU/CTPL-SR will continue to be an essential shared resource to
facilitate high-quality translational research within the OSUCCC, especially given the current growth plans that
include: a) recruitment for both immuno-oncology (Pelotonia Institute of Immuno-Oncology) and translational
genomics; and b) commitments to medical oncology, hematology and gynecologic oncology for recruitments and
corresponding expectations for increased INDs and trial accruals. The annual budget of the CTU-CTPL-SR is
$1,104,344, yet the CCSG request is $126,251. As such, the CTU/CTPL-SR leverages extensive institutional
support and seeks only 11.4% support from CCSG funds.

## Key facts

- **NIH application ID:** 10333293
- **Project number:** 5P30CA016058-46
- **Recipient organization:** OHIO STATE UNIVERSITY
- **Principal Investigator:** GREGORY A OTTERSON
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $179,411
- **Award type:** 5
- **Project period:** 1997-09-12 → 2025-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10333293

## Citation

> US National Institutes of Health, RePORTER application 10333293, Shared Resource 05: Clinical Treatment Unit/ Clinical Trials Processing Lab (CTU/CTPL-SR) (5P30CA016058-46). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10333293. Licensed CC0.

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