SHARED RESOURCE MANAGEMENT PROJECT SUMMARY/ABSTRACT The central goal of Shared Resource Management (SRM) is to ensure that the seven Shared Resources (SRs) supported by the Chao Family Comprehensive Cancer Center (CFCCC) provide cutting-edge, cost-effective, easily-accessible services that facilitate high-impact cancer research. CFCCC SR services span the spectrum from patient-focused behavioral science to cellular and molecular aspects of cancer, providing high quality services that operate at the leading edge of their respective disciplines. In support of these services, the CFCCC provides financial support, management and oversight, ensuring that SRs offer state-of-the-art technologies, services and consultation. In the current funding period, the CFCCC has provided $1.12M for equipment costs alone. The overall total CFCCC contribution to support the SRs ($6.2M) was matched by institutional support from UC Irvine (UCI; $4.30M). The CFCCC directly manages one SR and jointly governs the other six with UCI academic units. Governance mechanisms and ongoing monitoring are in place to ensure that SRs are adequately supported and that they follow NCI guidelines for Cancer Center member accessibility, cost-effectiveness, and quality. The SRs are led by CFCCC Deputy Director (DD) Marian Waterman, PhD, with leadership assistance from the Associate Director (AD) for Administration & Finance Christine Hui, MPH. Together the DD and AD oversee and monitor the development and effectiveness of technologies and services offered to CFCCC members. Waterman and Hui are assisted by the ADs for Basic Science, Clinical Science, and Population Science & Cancer Control. The SRM team works on behalf of CFCCC membership to ensure priority access to technologies, services, and expertise that enhance scientific interaction and productivity; to monitor the stability, reliability, cost- effectiveness, and quality of research resources; and to evaluate the scientific needs of cancer center members and facilitate the development and/or purchase of new technologies, services and methodologies. During the next funding period, the CFCCC plans to develop a new SR in Mass Spectrometry.