# Medical Imaging Technology Development Core

> **NIH NIH P20** · UNIVERSITY OF OKLAHOMA · 2022 · $452,682

## Abstract

ABSTRACT – Medical Imaging Technology Development Core 
 The objective of the Medical Imaging Technology Development Core (MITDC) is to build an infrastructure to 
support research of the junior research project leaders (RPLs) and overarching goal of this COBRE. The Core 
will be built based on the OU Advanced Medical Imaging Center (OU-AMIC), which has been supported by both 
the Gallogly College of Engineering University of Oklahoma (OU) Norman campus and the Stephenson Cancer 
Center of OUHSC campus since 2012. OU-AIMC includes 5 research laboratories and an established network 
between the engineering and clinical expertise to facilitate the interdisciplinary research. OU-AIMC provides a 
solid foundation for this MITDC to provide important resource for RPLs and pilot project awardees of the COBRE. 
The MITDC Core has 3 Specific Aims. Aim 1: We will implement an interdisciplinary management plan to build 
an optimal infrastructure to support translational medical imaging related cancer research. The Core will be co- 
directed by an experienced engineer and a physician researcher. An advisory board of senior engineering and 
physician researchers will be established to guide the development and operation of the Core. Existing imaging 
equipment and other tools will be integrated to serve COBRE projects, along with equipment and services 
available by industry and clinical collaboration. Monthly brainstorming meetings, on demand tours, round table 
discussions, and biannual open house workshops will facilitate interaction between members of the Core and 
researchers on both OU Norman and OUHSC campuses. These activities will allow the Core to better understand 
researcher needs and provide opportunities for researchers to learn new imaging technologies that can benefit 
their research. Aim 2: We will design and develop a series of investigative imaging tools and testbeds to provide 
researchers fast and cost-effective methods to test their innovative research concepts. Using testbeds of new 
imaging modalities, the researchers will be able to acquire preliminary data to validate their hypotheses without 
the expensive and time-consuming development of a fully equipped laboratory. Based on the research areas of 
the initially selected RPL projects and other junior researchers in the COBRE pool, the testbeds will include, but 
are not limited to, phase-contrast X-ray imaging, X-ray fluorescence tomography, digital pathology scanners, 
and special optical imaging devices. Aim 3: We will build an integrated computer server/network and provide 
new computer-aided quantitative image feature analysis schemes and software to support the RPLs and other 
researchers to conduct large data and deep transfer learning-based Radiomics studies. This will improve the 
efficiency and consistency of developing and validating quantitative image markers and/or machine learning 
prediction models developed by different projects. In summary, MITDC will provide a uniq...

## Key facts

- **NIH application ID:** 10334983
- **Project number:** 1P20GM135009-01A1
- **Recipient organization:** UNIVERSITY OF OKLAHOMA
- **Principal Investigator:** Hong Liu
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $452,682
- **Award type:** 1
- **Project period:** 2022-02-15 → 2026-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10334983

## Citation

> US National Institutes of Health, RePORTER application 10334983, Medical Imaging Technology Development Core (1P20GM135009-01A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10334983. Licensed CC0.

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