Title: Determination of LMP744 (NSC 706744) Levels in Human Plasma and Urine Samples from an NCI Phase I Trial.POP: 04/10/2017 - 04/09/2018

NIH RePORTER · NIH · N02 · $134,113 · view on reporter.nih.gov ↗

Abstract

A series of indenoisoquinoline inhibitors of topoisomerase I have been extensively studied by the NCI, and two of these compounds (LMP400 and LMP 776) have previously been investigated in human clinical trials.

Key facts

NIH application ID: 10335107
Project number: 261201600022I-P00003-26100002-1
Recipient: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
Principal Investigator: JULIE EISEMAN
Activity code: N02
Funding institute: NIH
Fiscal year: 2021
Award amount: $134,113
Award type: —
Project period: 2017-04-10 → 2022-06-30