# Alterations and Renovations

> **NIH NIH P20** · SOUTH DAKOTA STATE UNIVERSITY · 2022 · $351,337

## Abstract

PROJECT SUMMARY – Alteration & Renovations
The South Dakota State University (SDSU) vivarium, known as the Animal Research Wing (ARW) will be
utilized by the research projects in the proposed BioSNTR-II. To efficiently, reliably, and responsibly conduct
animal experiments, the vivarium climate must be controlled within ranges consistent with compliance
standards and for animal welfare. In addition, efficient maintenance of animal house with use of an automatic
cage washer system is important for reducing costs and ensuring sustainability of the facility. Preliminary
analysis and planning by the Senior Mechanical Engineer and the Director of Energy Systems of South Dakota
State University Facilities and Services identified critically needed environmental control alterations and
renovations. For nine months of the year, the vivarium is not fully compliant with temperature or humidity
standards of the Office of Laboratory Animal Welfare for at least one day per week. This is because the
environmental control system is unable to maintain room temperature and room humidity simultaneously within
compliance ranges. The origin of this problem stems from incorrect sizing of ventilation and humidification
equipment from the initial construction. Therefore, the goal of this alterations and renovations request is to
upgrade several components of the environmental system to increase simultaneous control of temperature and
humidity in rooms that BioSNTR-II will utilize. Additionally, since the time of the first submission, of this
proposal, SDSU has initiated retrofits to the building, thereby lowering the costs. In this revised application, we
are requesting funds to complete these renovations. We are also requesting support to replace the aging
animal cage washer system to ensure efficient, reliable and cost-effective implementation for the BioSNTR-II
project and future biomedical research at SDSU. These upgrades will increase the efficiency and reliability of
the SDSU vivarium for responsible biomedical research using animal models.

## Key facts

- **NIH application ID:** 10335536
- **Project number:** 1P20GM135008-01A1
- **Recipient organization:** SOUTH DAKOTA STATE UNIVERSITY
- **Principal Investigator:** Michele Rene Mucciante
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $351,337
- **Award type:** 1
- **Project period:** 2022-03-20 → 2027-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10335536

## Citation

> US National Institutes of Health, RePORTER application 10335536, Alterations and Renovations (1P20GM135008-01A1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10335536. Licensed CC0.

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