PROJECT SUMMARY – CORE A, ADMINISTRATIVE CORE The Administrative Core, will build on an established research center administrative architecture to support the proposed BioSystems Networks and Translational Research center-Investigating Inflammation (BioSNTR-II). This infrastructure includes an effective and proven administrative team that will coordinate fiscal and scientific management across South Dakota State University (SDSU) and partner institutions. The Administrative Core will support the development and transition to independence of each project leader through mentorship, efficient research administration, development of resources, and support of professional career development. This core will focus its efforts on fostering a supportive and collaborative research environment and culture intent on advancing biomedical research at SDSU. These activities will include organizing monthly seminars and speaker exchanges, annual research symposia, all center-associated travel, workshops, and training opportunities. Additionally, the Administrative Core will manage and oversee a pilot project program to promote the development of new center research projects. All BioSNTR-II resources including the development of each of the research support cores will be coordinated by the Administrative Core to ensure financial and personnel needs are met and newly developed tools and techniques are appropriate for use by the COBRE research projects. Finally, the Administrative Core will work with both the SDSU administration and implement recommendations from the External Advisory Board to conduct constructive evaluations of the research projects and cores, overall development of the center, and faculty development goals. This core has experienced personnel, established operating procedures and policies, and the thorough evaluation and review structures necessary for the effective implementation of BioSNTR-II.