# The impact of a resistance training intervention on blood pressure control in older adults with Sarcopenia

> **NIH NIH K01** · UNIVERSITY OF ILLINOIS AT CHICAGO · 2021 · $54,000

## Abstract

PROJECT SUMMARY/ABSTRACT
In response to PA-20-272 (NOT-OD-20-054), this request is submitted for an administrative supplement to the
mentored career development award, K01HL148503 funded through the National Heart, Lung, And Blood
Institute of the NIH. The proposed supplement falls within the scope of the parent grant, which focuses on
addressing current gaps in the literature regarding the understanding of high blood pressure due to sarcopenia
and provides new evidence for the discernable relationship between low muscle strength and blood pressure in
sarcopenia, and effective non-pharmaceutical treatment approaches. Due to her critical life event, Dr. Laddu is
at a critical juncture where time constraints and limited staff to support training and research responsibilities have
led to critical gaps in career development and research productivity. The objectives of the supplement are to
ensure the continuity of Dr. Laddu’s career development and research training and facilitate transition to research
independence, following her critical life event. This application describes the negative implications of Dr. Laddu’s
critical life event on her career development and research productivity. This application further outlines Dr.
Laddu’s request for additional resources that will be necessary to address gaps in productivity occurring as a
direct consequence of her critical life event, and sufficient to facilitate Dr. Laddu’s return to full research
productivity by the end of the supplement period. The specific request for supplemental research support is
twofold (1) to hire additional personnel to oversee the methodological delivery of day-to-day operations of the
study including coordinating study protocol activities and ensuring quality of data collection; (2) to support
additional biostatistical services needed to assist with data analyses and manuscript preparation related to Aim
1 and Aim 2 of the parent grant. With support from this Program, Dr. Laddu will be well positioned to fulfill gaps
in productivity that occurred as a negative consequence of the critical life event and resume to full research
productivity by the end of the supplemental period. Ensuring continuity of research will further support Dr. Laddu’s
project milestones and long-term goals of developing more definitely powered R-level applications to evaluate
efficacy of the intervention and potential therapeutic mechanisms by which resistance exercise impacts vascular
health in older adults with varying debilitating conditions. Importantly, this supplement program will support Dr.
Laddu’s efforts to engage in career development and research activities that are critical to increasing her
research productivity and scholarly visibility, and for preserving her progress towards research independence as
an expert trialist in health promotion and chronic disease prevention in older adult populations.

## Key facts

- **NIH application ID:** 10337878
- **Project number:** 3K01HL148503-02S1
- **Recipient organization:** UNIVERSITY OF ILLINOIS AT CHICAGO
- **Principal Investigator:** Deepika Laddu
- **Activity code:** K01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $54,000
- **Award type:** 3
- **Project period:** 2019-08-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10337878

## Citation

> US National Institutes of Health, RePORTER application 10337878, The impact of a resistance training intervention on blood pressure control in older adults with Sarcopenia (3K01HL148503-02S1). Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/grant/nih/10337878. Licensed CC0.

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