# Increasing COVID-19 Vaccine Uptake among Latinos through a Targeted Clinical and Community-behavioral Intervention

> **NIH NIH R01** · SAN DIEGO STATE UNIVERSITY · 2022 · $633,539

## Abstract

Project Summary/Abstract
The United States currently has the highest COVID-19 infection and related mortality rates in the world. In
California, Latinos account for the highest percent of COVID-19 cases (58.9%) and deaths (47.3%) and are
disproportionately represented in occupations deemed as ‘essential’. Latinos also suffer from higher rates of
poverty and chronic disease which places them at greater risk of COVID-19 infection and related complications.
In collaboration with Family Health Centers of SD (FHCSD) and working with Community Health Workers (aka,
promotores/as), we will implement a multilevel intervention to increase COVID-19 vaccine completion rates and
see faster vaccination uptake among Latinos. A total of 10 clinics will be randomized to either a Standard Clinical
Practice consisting of standard clinic-based strategies to promote COVID-19 vaccine uptake among patients or
a Multilevel Intervention consisting of an individualized/tailored intervention delivered by Health Educators
working within the clinics plus a multi-component community intervention delivered by community promotores.
This project will test the immediate and short-term effectiveness of the multilevel intervention to increase COVID-
19 vaccine uptake. In addition, we will test the effectiveness of the proposed intervention on long-term behavioral,
mental, and physical health outcomes. Lastly, this project will assess implementation outcomes including
program acceptability and feasibility by patients and clinic staff and community environment. This study aims to
increase the uptake of completing the COVID-19 vaccine in a population that has exceptionally high rates of
morbidity and mortality due to COVID-19. We will harness our research team’s extensive experience in
developing multi-level interventions working with Health Educators and promotores to promote behavior change
among Latinos, and leverage a strong community-academic collaboration that maximizes community impact and
sustainability. This research will lead to the development of sustainable and scalable community-academic
models designed to respond quickly, efficiently, and effectively to both this existing and future public health
threats.

## Key facts

- **NIH application ID:** 10345813
- **Project number:** 1R01MD016880-01
- **Recipient organization:** SAN DIEGO STATE UNIVERSITY
- **Principal Investigator:** Noe Cuauhtemoc Crespo
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $633,539
- **Award type:** 1
- **Project period:** 2022-08-21 → 2025-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10345813

## Citation

> US National Institutes of Health, RePORTER application 10345813, Increasing COVID-19 Vaccine Uptake among Latinos through a Targeted Clinical and Community-behavioral Intervention (1R01MD016880-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10345813. Licensed CC0.

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