# Global Network for Women's and Children's Health Research Data Coordinating Center

> **NIH NIH U24** · RESEARCH TRIANGLE INSTITUTE · 2021 · $241,469

## Abstract

The aim of the “COVID-19 prevalence during pregnancy and pregnancy outcomes in 8
LMIC: A Global Network for Women's and Children's Health” study is to determine the
prevalence of COVID-19 antibodies in pregnant /recently delivered women in 8 Global
Network sites (in DRC, Kenya, Zambia, Bangladesh, India [2 sites], Pakistan and
Guatemala) and its association with pregnancy outcomes. RTI International serves as
the study data coordinating center. Specifically, the study will determine the prevalence
of COVID-19 antibodies in pregnant/recently delivered women in 8 Global Network sites
using antibody testing; compare the maternal, fetal and neonatal outcomes of COVID-19
antibody positive women vs. antibody negative women (low birth weight, preterm birth,
fetal growth restriction, stillbirth and neonatal mortality); and will assess knowledge,
attitudes and practices of pregnant women related to COVID-19 during pregnancy. This
will be a prospective, population-based, cohort study conducted of 20,000 women which
will be conducted within the Global Network's Maternal and Newborn Health Registry
(MNHR), a population-based observational study, over a 12-month study period.
Following enrollment in the MNHR, women will be requested to consent for the COVID-
19 study which may include a blood sample collected at first antenatal care visit (4 sites)
and/or at delivery (all sites). All women enrolled will also have pregnancy outcomes
collected at delivery and 6-weeks postpartum. Maternal samples will be assessed for
COVID-19 antibodies, using the same testing analyses methodology across all study
sites, coordinated and supported through RTI International. Analyses will be conducted
to assess the prevalence of COVID-19 antibodies in the population, and to assess the
association of antibodies with maternal and newborn outcomes.

## Key facts

- **NIH application ID:** 10348262
- **Project number:** 3U24HD092094-04S1
- **Recipient organization:** RESEARCH TRIANGLE INSTITUTE
- **Principal Investigator:** Elizabeth M McClure
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $241,469
- **Award type:** 3
- **Project period:** 2021-02-10 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10348262

## Citation

> US National Institutes of Health, RePORTER application 10348262, Global Network for Women's and Children's Health Research Data Coordinating Center (3U24HD092094-04S1). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10348262. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*