# Research Core

> **NIH NIH P20** · CLEMSON UNIVERSITY · 2022 · $408,593

## Abstract

SUMMARY
The ability to generate, store and analyze high throughput genomic data is critical for many aspects of modern
biology, and especially for human genetics. The Clemson University Genomics and Bioinformatics Facility
(CUGBF) provides small to moderate scale genome analysis and customized bioinformatics services. The
Clemson University Center for Human Genetics Genome Sciences Laboratories (CUCHG-GSL) supports in-
house high throughput, large scale genome analysis, including third generation single molecule long-read
sequencing and single cell analyses, as well as custom bioinformatic and statistical analyses of genomic data.
The COBRE in Human Genetics will expand the scope of genomics and bioinformatics at Clemson University
and the State of South Carolina by combining and expanding the genomics, bioinformatics and computational
infrastructure and personnel of the CUGBF and the CUCHG-GSL under the single umbrella of an enhanced
CUGBF. The expanded CUGBF will span the spectrum of next generation sequencing platforms, provide
custom bioinformatics and statistical analyses and advice on experimental design, and genomics and
bioinformatics seminars and workshops. The enhanced CUGBF will thus provide the infrastructure, project
guidance and supervision, and training to empower COBRE in Human Genetics Research and Pilot Project
Leaders and their laboratory groups to fully deploy extant and emerging genomic and computational
technologies in their research programs. These services will also be available for all Clemson University faculty
and their research groups as well as faculty in sister institutions in South Carolina. In addition, the enhanced
CUGBF will host monthly genomics and bioinformatics seminars and hands-on workshops to train students,
postdoctoral fellows and faculty to become self-sufficient in obtaining and analyzing genomics data. The
enhanced CUGBF thus fills three critical needs for the wide scale adoption of modern genomics and
bioinformatics research in an Institutional Development Award state: (1) local availability of genomics and
computational infrastructure; (2) provision of molecular biology and bioinformatics services to investigators new
to such large scale analyses; and (3) training researchers to become self-sufficient in obtaining and analyzing
genomics data.

## Key facts

- **NIH application ID:** 10348699
- **Project number:** 5P20GM139769-02
- **Recipient organization:** CLEMSON UNIVERSITY
- **Principal Investigator:** TRUDY F. MACKAY
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $408,593
- **Award type:** 5
- **Project period:** 2021-02-10 → 2026-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10348699

## Citation

> US National Institutes of Health, RePORTER application 10348699, Research Core (5P20GM139769-02). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10348699. Licensed CC0.

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