# Randomized-controlled trial of virtual reality for chronic low back pain to improve patient-reported outcomes and physical activity: Understanding Patient Predictors of Response

> **NIH NIH UH3** · CEDARS-SINAI MEDICAL CENTER · 2021 · $137,134

## Abstract

PROJECT SUMMARY
Although digital health technologies are now widely available for both therapeutic and
monitoring applications, there are wide variations in patient knowledge, attitudes, beliefs, and
preferences regarding uptake and effectiveness of digital health interventions. In addition, there
are sociodemographic variations in willingness to engage in digital health studies, both for
chronic pain and other common disorders. However, there have been few efforts to
systematically examine patient-level predictors of digital health uptake and benefit among
diverse patients with chronic pain. In this pilot study, we will employ mixed methods to examine
variations in engagement and benefit among diverse participants in a large NIH-sponsored trial
examining benefits of virtual reality (VR) for chronic lower back pain (cLBP).

## Key facts

- **NIH application ID:** 10350470
- **Project number:** 3UH3AR076573-03S2
- **Recipient organization:** CEDARS-SINAI MEDICAL CENTER
- **Principal Investigator:** Brennan Spiegel
- **Activity code:** UH3 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $137,134
- **Award type:** 3
- **Project period:** 2019-09-25 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10350470

## Citation

> US National Institutes of Health, RePORTER application 10350470, Randomized-controlled trial of virtual reality for chronic low back pain to improve patient-reported outcomes and physical activity: Understanding Patient Predictors of Response (3UH3AR076573-03S2). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10350470. Licensed CC0.

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