# Use of advanced analytics to understand brain-behavior screen media activity relationships in ABCD data

> **NIH NIH RF1** · YALE UNIVERSITY · 2021 · $1,303,989

## Abstract

Project Summary/Abstract
Growing up in a media-saturated world, the current generation of children and adolescents spend on average 6-
9 hours each day on screen media activities (SMAs). Therefore, SMA is a topic of considerable concern in the
USA and elsewhere. Given changes in digital technologies and their usage over the past several decades, there
is a significant gap in our understanding of shorter- and longer-term impacts of SMA on brain-behavior
relationships. Prior studies suggest that problematic patterns of internet use (e.g., internet gaming disorder
(IGD)) are linked to brain structural and functional alterations. However, the majority of research focuses on
identifying individual SMA-related brain regions, which provide a crude approximation or an incomplete view of
factors underlying these complex behaviors. We believe that consideration of brain networks is crucial to
understanding neurodevelopmental mechanisms of SMA and associated behaviors. In this application, we
propose to use data from the longitudinal Adolescent Brain Cognitive Development (ABCD) study to investigate
network-level neural substrates linked to SMA, sleep disturbances and other clinically relevant measures.
Multiple advanced analytical approaches will be used to extract novel features at both structural and functional
levels. For example, the Joint and Individual Variance Explained (JIVE) method will be used to extract biologically
meaningful cortical-subcortical covariation patterns. In this project, we aim to (1) establish relationships between
SMA and brain structural and functional development in children aged 9-10 years; and, (2) investigate a potential
mediating role of sleep disturbances on the relationship between SMA and brain structural and functional
development. Our study uses innovative analytical methods to understand complex SMA-brain-behavior
relationships in a large, developing sample recruited at 21 sites across the United Sates. Results from this
application should provide important insights into understanding the neural processes involved in SMA, sleep
disturbances and other clinically relevant behaviors within a developmental context.

## Key facts

- **NIH application ID:** 10358692
- **Project number:** 1RF1MH128614-01
- **Recipient organization:** YALE UNIVERSITY
- **Principal Investigator:** Marc N Potenza
- **Activity code:** RF1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,303,989
- **Award type:** 1
- **Project period:** 2021-09-10 → 2026-03-09

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10358692

## Citation

> US National Institutes of Health, RePORTER application 10358692, Use of advanced analytics to understand brain-behavior screen media activity relationships in ABCD data (1RF1MH128614-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10358692. Licensed CC0.

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