# Development and Evaluation of a Mobile Health Intervention to Support Healthful Dietary Choices in Older Persons with Frailty

> **NIH NIH K23** · UNIVERSITY OF WASHINGTON · 2022 · $151,095

## Abstract

PROJECT SUMMARY
Frailty is common, serious and potentially modifiable geriatric syndrome. Although evidence accumulate that
nutritional supplements improve functional measures in persons with frailty, the interventions are carried out in
a controlled setting and might have limited legacy effect. Recent dietary guidelines suggest that overall
adherence to a healthful diet is instrumental for a sustainable health behavioral change. Among available
healthful dietary patterns Mediterranean Diet (MedD) is well studied in aging because of its anti-inflammatory
and glucomodulating effects. Given disruptions in insulin sensitivity, inflammation, and muscle metabolism
observed in frailty, MedD is ideally poised to improve functional outcomes in this population. However,
limitations exist that commonly used behavioral strategies to facilitate healthful dietary choices are not scalable
and might be inadequate for use with individual patients. In fact, few individualized dietary interventions have
been designed to empower and enable older and frail persons to self-manage their heath. Mobile health
technologies, including apps, with increased sophistication and capacity for accommodating multiple self-
management features (e.g., self-monitoring, interactive feedback) hold great promise to heighten older
person's involvement in self-management. However, to date, few of these mobile health (mHealth) approaches
were developed for and engaged vulnerable older adults. The proposed research will use rapid iterative
methodology to develop with end users, easy to use and intuitive mHealth system that will allow self-
monitoring, information exchange and promote adherence to MedD. This work a clear trajectory for patient-
oriented research building upon candidate's previous epidemiological and intervention work. In former he
explored the impact of nutritional and metabolic factors on frailty risk and prognosis finding that increased
adherence to MedD, independently of other nutritional measures, relate to better health in persons with frailty.
In latter, he successfully employed a mobile intervention in behavioral change context in older and frail adults.
This preliminary work provided conceptual and empirical ground for the proposed project. The candidate's
career goal is to become an independent researcher and lead the development of technology augmented
interventions, suitable for older and vulnerable populations, that facilitate self-management and promote
functional independence. The career development plan integrates didactic coursework with practical mentored
research experience to achieve the following training goals: 1) obtain training in nutritional science; 2) develop
skills in development of person-centered mHealth interventions; 3) achieve capacity to effectively conduct
clinical trials in mobile health and patient-oriented context; 4) improve competencies in clinical geriatrics; 5)
obtain proficiency with scientific writing and grantsmanship. The candida...

## Key facts

- **NIH application ID:** 10361417
- **Project number:** 5K23AG059912-04
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** Oleg Zaslavsky
- **Activity code:** K23 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $151,095
- **Award type:** 5
- **Project period:** 2019-04-15 → 2023-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10361417

## Citation

> US National Institutes of Health, RePORTER application 10361417, Development and Evaluation of a Mobile Health Intervention to Support Healthful Dietary Choices in Older Persons with Frailty (5K23AG059912-04). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10361417. Licensed CC0.

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