# Admin Core - Autophagy Modulators as Novel Broad-Spectrum Anti-Infective Agents

> **NIH NIH U19** · UT SOUTHWESTERN MEDICAL CENTER · 2022 · $637,166

## Abstract

Project Summary – Administrative Core 
The Administrative Core will provide the requisite infrastructure to achieve the overall research objectives of the 
CETR. Effective scientific management and coordination by the Administrative Core will provide direction, 
oversight, and quality control for the research activities of each Project, and will maximize collaboration and 
exchange from all participating groups. Clear scientific leadership and direct communication by the 
Administrative Core will ensure optimal and transparent utilization of resources that promotes productive long- 
term relationships. The Administrative Core will promote data sharing, integration of projects, and 
communication, which will leverage the expertise of each member of the CETR to expedite discovery and 
achievement of the research goals. The Administrative Core will achieve several of these goals by providing a 
coherent stream of communication, which will begin by establishing monthly meetings between Program 
participants under the guidance of the Program Director. These meetings will be held through video 
teleconference and will promote data exchange, evaluation of progress and planning as it relates to the goals of 
the program and aims of individual projects. Each meeting will include discussion and analysis of results, goals 
and progress, as well as a forum for negotiation of key strategic decisions. The Administrative Core also will 
foster communication and organizational structure through preparation of financial reports and documents (e.g., 
progress reports) for the NIH. The Administrative Core will have specific financial responsibilities and obligations 
particularly as it relates to shared activities among CETR members. This will include costs associated with 
Scientific Advisory Committee travel and clerical/communication programs directly related to the CETR. Through 
these activities, the Administrative Core will ensure an interactive and collaborative environment, exchange of 
reagents and data, and foster a cohesive relationship among PIs of the CETR, which will enhance our direct 
goal of further developing novel autophagy-directed anti-infectives against NIAID priority pathogens.

## Key facts

- **NIH application ID:** 10364722
- **Project number:** 5U19AI142784-04
- **Recipient organization:** UT SOUTHWESTERN MEDICAL CENTER
- **Principal Investigator:** HERBERT W VIRGIN
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $637,166
- **Award type:** 5
- **Project period:** 2019-03-15 → 2024-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10364722

## Citation

> US National Institutes of Health, RePORTER application 10364722, Admin Core - Autophagy Modulators as Novel Broad-Spectrum Anti-Infective Agents (5U19AI142784-04). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10364722. Licensed CC0.

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