# Data Coordination for the AMP Autoimmune and Related (AR) Knowledge Portal

> **NIH NIH U24** · SAGE BIONETWORKS · 2021 · $408,537

## Abstract

Project Summary/Abstract
The Accelerating Medicines Partnership (AMP) program is a public private partnership started in
2014 to transform the way diagnostics and treatments are developed. Partners work together to
increase the number of diagnostics and therapies while reducing the cost of development in
several disease areas. The program uses an open science paradigm to support early, iterative
integration of resources and evaluation of findings across multiple independent teams. In the
AMP in Alzheimer’s Disease Target Discovery and Preclinical Validation project (AMP-AD) this
open approach was designed to improve observations through integration of multiple data
sources, to increase confidence in outcomes through transparency, reproducibility, and
benchmarking of methods and to accelerate evaluation of nominated AD targets by aggregating
evidence and expertise across the field. Cross-consortium activities are supported by the Data
Coordination Center (DCC) led by Sage Bionetworks. Functions include resource sharing,
providing analytical workspaces for researchers to perform cross-team analytical projects, and
coordinated evaluation across the program of research outcomes. This supplement is designed
to extend the activities of the AMP-AD DCC to support the AMP Autoimmune disorders of
rheumatoid arthritis and systemic lupus erythematosus (SLE) (AMP-RA/SLE).

## Key facts

- **NIH application ID:** 10374660
- **Project number:** 3U24AG061340-03S3
- **Recipient organization:** SAGE BIONETWORKS
- **Principal Investigator:** LARA M MANGRAVITE
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $408,537
- **Award type:** 3
- **Project period:** 2018-09-30 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10374660

## Citation

> US National Institutes of Health, RePORTER application 10374660, Data Coordination for the AMP Autoimmune and Related (AR) Knowledge Portal (3U24AG061340-03S3). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10374660. Licensed CC0.

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