# Gnotobiotics, Microbiology and Metagenomics Core

> **NIH NIH P30** · BOSTON CHILDREN'S HOSPITAL · 2022 · $277,496

## Abstract

Project Summary:
The Gnotobiotics, Microbiology and Metagenomics Core (Core D), supports investigators studying
functional roles of the microbiota in health and disease. Core D has supported >100 groups interested in
evaluating mechanisms of action by which the host’s microbiota affects host physiologic and
pathophysiologic processes.
Our resources include a Microbiology Unit for microbiologic culturing, phenotyping, analysis of primary
samples for microbial metabolite profiles, and develop defined consortia for functional studies, a Clinical Lab
(CLIA) Unit to support microbiome-focused clinical trials, a Molecular Unit for sequence-based analyses, a
Gnotobiotic (germfree) mouse facility for in vivo studies in animal models, a Metabolic Unit to support
mouse metabolic cage, body composition and metabolism studies, and a Computational Unit which
undertakes novel algorithmic development to evaluate longitudinal dynamics of the microbiota and assist
users in experimental design for host-microbiota studies.
Core D provides support to multiple academic centers in the greater Boston area.

## Key facts

- **NIH application ID:** 10378466
- **Project number:** 5P30DK034854-37
- **Recipient organization:** BOSTON CHILDREN'S HOSPITAL
- **Principal Investigator:** LYNN BRY
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $277,496
- **Award type:** 5
- **Project period:** 1997-09-01 → 2026-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10378466

## Citation

> US National Institutes of Health, RePORTER application 10378466, Gnotobiotics, Microbiology and Metagenomics Core (5P30DK034854-37). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10378466. Licensed CC0.

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