# Cancer Control and Survivorship Program

> **NIH NIH P30** · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · 2022 · $70,177

## Abstract

PROJECT SUMMARY/ABSTRACT—Cancer Control and Survivorship Program 
The overarching goal of the Cancer Control and Survivorship Program (CCSP) is to conduct highly innovative 
clinical, genetic, and observational research, and translate our findings into effective strategies to avert or 
mitigate treatment-related complications and improve the quality of life of childhood cancer survivors. Drs. Leslie 
L. Robison, chair of the Department of Epidemiology and Cancer Control, and Melissa Hudson, director of the 
Division of Cancer Survivorship, lead the Program. Their leadership roles in the CCSP's two NCI-funded cohorts, 
St. Jude Lifetime Cohort Study (SJLIFE) and the Childhood Cancer Survivor Study (CCSS), have facilitated 
seminal discoveries characterizing the magnitude and scope of morbidity of the childhood cancer experience, 
including the resulting burden of chronic disease and subsequent neoplasms and their contribution to premature 
mortality. Knowledge gained from this research has influenced the design of contemporary pediatric cancer 
treatment strategies and provided critical data to guide health surveillance and health preserving interventions 
for long-term survivors. The CCSP is structured around an extensive shared research infrastructure designed to 
support and enhance the research conducted by Program members. This infrastructure reflects a combination 
of departmental-focused resources, augmented by institutional and SJCCC-specific resources plus clinical 
services external to the institution. The CCSP has a total of 16 members (11 Full and 5 Associate), representing 
the Departments of Epidemiology & Cancer Control, Oncology, Psychology, Global Pediatric Medicine, and 
Pediatric Medicine. The design and conduct of innovative research is facilitated by 7 discipline-specific CCSP 
working groups: Neurosciences, Cardiopulmonary, Endocrine-Reproductive, Genetics, Global Outcomes, 
Psychosocial-Behavioral, and Epidemiology-Biostatistics, who meet on a regular schedule (bi-weekly or 
monthly). During the current grant period (2013-2017), CCSP members have actively engaged in intra- and inter- 
programmatic research collaborations. Research publications by CCSP members totaled 424 and demonstrate 
the highly collaborative nature of the Program with 50% reflecting an intra-programmatic and 25.9% inter- 
programmatic collaboration. During the current funding period, CCSP members initiated/conducted trials 
addressing approaches to enhance health screening for at-risk survivors, promote positive health behaviors, 
remediate treatment-induced cognitive deficits, and reduce fatigue, contributing a total of 2283 enrollments to 
interventional non-therapeutic trials. Many of these trials reflect a direct translation of observational research 
conducted by CCSP members. CCSP members have participated in a wide variety of multi-group collaborations 
(involving more than 20 NCI-designated Cancer Centers, the NCI Division of Cancer Epidemiology ...

## Key facts

- **NIH application ID:** 10378575
- **Project number:** 5P30CA021765-43
- **Recipient organization:** ST. JUDE CHILDREN'S RESEARCH HOSPITAL
- **Principal Investigator:** Gregory Armstrong
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $70,177
- **Award type:** 5
- **Project period:** 1997-04-01 → 2024-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10378575

## Citation

> US National Institutes of Health, RePORTER application 10378575, Cancer Control and Survivorship Program (5P30CA021765-43). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10378575. Licensed CC0.

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