# NRG Oncology Network Group Operations Center

> **NIH NIH U10** · NRG ONCOLOGY FOUNDATION, INC. · 2022 · $5,477,432

## Abstract

Member Site Core Abstract 
NRG Oncology (NRG) has established a large and diverse membership that includes 220 Tier 1 
(Main Members) and 1188 Tier 2 enrolling sites. NRG Main Members and affiliates are located 
in all 50 states, Washington, DC, and Puerto Rico. There are 16 Canadian Main Members and 
12 Non-North American Main Members located in 8 countries. NRG Oncology has the largest 
membership base of the groups in the NCI National Clinical Trials Network (NCTN), and NRG 
members also contribute the highest percentage of patients to the NCTN. For the period of 
March 1, 2014, through August 31, 2017, NRG trial accrual plus accrual to other NCTN group 
trials credited to NRG by its members represents approximately a third of the total NCTN 
accrual for that grant period. Of the 9,000 American patients enrolled on NRG trials during this 
time period, 12.7% self-identified as of African descent, 8.0% as Hispanic or Latino, and 1.3% 
as Native Hawaiian, other Pacific Islander, Native American, or Alaska native.. NRG has 
developed an audit program which is in compliance with the guidelines established by the NCI's 
Clinical Trials Monitoring Branch (CTMB). In addition, NRG carefully evaluates protocol accrual 
and data quality, a practice which enables the group to identify and intervene when 
underperforming centers are identified. NRG has developed a variety of accrual enhancement 
efforts including: the NRG Protocol Support Committee that reviews all proposed protocols 
relative to nursing and non-nursing matters; the NRG Health Disparities Committee whose 
primary aim is to increase enrollment of underrepresented populations to NRG trials; the 
Communications Committee which provides updates to the NRG members and general public 
promoting NRG activities and trials; the Center for Innovation in Radiation Oncology (CIRO) 
which assists NRG members with radiotherapy and imaging quality assurance process, 
including site qualification, credentialing and case reviews; and a Toll-Free 800 Line available 
for NRG members to obtain answers to protocol related questions. NRG cancer disease site 
committees have developed successful programs for patients with rare tumors and trials that 
provide an opportunity to enroll adolescent and young adult patients.

## Key facts

- **NIH application ID:** 10378672
- **Project number:** 5U10CA180868-09
- **Recipient organization:** NRG ONCOLOGY FOUNDATION, INC.
- **Principal Investigator:** NORMAN WOLMARK
- **Activity code:** U10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $5,477,432
- **Award type:** 5
- **Project period:** 2014-04-17 → 2025-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10378672

## Citation

> US National Institutes of Health, RePORTER application 10378672, NRG Oncology Network Group Operations Center (5U10CA180868-09). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10378672. Licensed CC0.

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