# Administration Core

> **NIH NIH U54** · STANFORD UNIVERSITY · 2021 · $1,089,399

## Abstract

While genes per se are not an adequate singular foundation for understanding racial and ethnic health
disparities, the potential of differential environments—including treatments—interacting with a differential
complement of genes in different subgroups does constitute a fertile context for the study of health disparities.
At Stanford, we have in place outstanding strengths in the three critical academic elements requisite to form a
coordinated, sustainable, and far-reaching research to practice collaboration to address racial and ethnic
health disparities with this focus: 1) Extensive experience both with laboratory assessment of genetic markers
and their relationships to both disease risk and treatment relevance, 2) Social disparities researchers,
spanning epidemiology, evolutionary biology, health services research and economics, and 3) Novel and
outstanding analytic and high-performance computing capabilities, recently consolidated in our Department of
Biomedical Data Science. Under the auspices of our new Stanford Center for Population Health Sciences, we
have recently redoubled our investments in Community Impact. It is in this context that we propose the
following overarching aims for this U54 application:
Specific Aim 1: Draw together the three principal scientific domains into new working relationships to achieve
the aims of each of the three proposed research projects while evolving into an integrated and sustainable
science “team” able to take on novel pilot projects proposed by our consortium partners, and sister Centers
around the country, while expanding our own portfolio of precision health research focusing on health
disparities over time.
Specific Aim 2: Availing the Consortium and Implementation Cores, develop and expand relationships with
our initial research partners to facilitate critical bidirectional research relationships in the community, starting
with the three proposed projects and maturing into a broad, sustainable nexus of partnerships to ensure
inclusion of further adversely impacted populations as research goes forward.
Specific Aim 3: Develop broad experience with “translation” of genetic and biologic information within different
racial and ethnic populations to optimize the application of such precision health approaches to reduce ethnic
and racial disparities where such approaches are most relevant.

## Key facts

- **NIH application ID:** 10380524
- **Project number:** 3U54MD010724-05S3
- **Recipient organization:** STANFORD UNIVERSITY
- **Principal Investigator:** MARK RICHARD CULLEN
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,089,399
- **Award type:** 3
- **Project period:** 2016-04-11 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10380524

## Citation

> US National Institutes of Health, RePORTER application 10380524, Administration Core (3U54MD010724-05S3). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10380524. Licensed CC0.

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