# 4/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries

> **NIH NIH U01** · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2021 · $161,402

## Abstract

Project Summary
This proposal is for a supplement to support the aims of the Populations Underrepresented in
Mental illness Association Studies (PUMAS) Project, an international collaboration of
investigators from the US, South America and Africa focused on large-scale psychiatric genetic
research in populations of Latin-American and African descent. PUMAS aims to discover new
genes for schizophrenia and bipolar disorder; it will dramatically increase the diversity of genetic
discovery efforts, an important step towards reducing health disparities; and it will expand the
scope of psychiatric genomics by discovering similarities and differences in genetic architecture
of schizophrenia and bipolar disorder across diverse ancestries and environments. The sheer
scope of the project will strain the resources of existing biosample repositories. This supplement
will advance the overall project by supporting the processing at the UCLA Neuroscience
Genomics Core (UNGC) biosample repository of samples from a portion of project participants
(those in Coastal Colombia and Southern California). The supplement will support the UNGC in
transporting samples to the repository, extracting and storing DNA, shipping DNA to the project’s
genomics core, and maintaining the informatics system that will enable it to provide samples to
qualified investigators.

## Key facts

- **NIH application ID:** 10383005
- **Project number:** 3U01MH125042-02S1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA LOS ANGELES
- **Principal Investigator:** NELSON B. FREIMER
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $161,402
- **Award type:** 3
- **Project period:** 2020-09-14 → 2025-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10383005

## Citation

> US National Institutes of Health, RePORTER application 10383005, 4/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries (3U01MH125042-02S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10383005. Licensed CC0.

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