# Daily dynamics of suicide risk, dysregulation, and sleep disruption across the transition to parenthood

> **NIH NIH F31** · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2021 · $37,850

## Abstract

PROJECT SUMMARY
Suicide accounts for 20-30% of maternal postpartum deaths, and is the second leading cause of death among
new mothers. Despite this national health crisis, current suicide research sorely neglects samples of pregnant
and postpartum women. There is urgent need to identify factors contributing to suicide risk in this population;
however, current perinatal research is limited by single-diagnostic approaches and poor measurement of self-
injurious thoughts and behaviors (SITBs). In addition, suicide research, in general, is in dire need of
methodological advancement, as predictive ability for suicide attempts has not improved. This project will
advance these fields of research by implementing an innovative multiple time-scale design that captures
repeated measures of women’s SITBs and relevant risk factors across the perinatal period. Specifically, sleep
disturbances (e.g., poor sleep quality, frequent nightly awakenings) and emotion dysregulation will be measured,
as they are well-established transdiagnostic risk factors for SITBs that are highly relevant across the perinatal
period. Pregnant women aged 18 to 39 who are enrolled in a parent R01 study (R01MH119070) will be recruited
for this project. They will wear wrist actigraphs for objective sleep-wake measurements and complete brief
morning and evening surveys on their sleep, emotion dysregulation, and SITBs for 7 days during the third
trimester, 6 weeks postpartum, and 4 months postpartum. These three time points are meaningful across the
perinatal period, as sleep outcomes decrease substantially by third trimester, depressive symptoms often
develop around 6 weeks postpartum, and there is virtually no research on women’s mental health beyond 3
months postpartum, despite evidence that most maternal self-harm deaths occur between 9 and 12 months
postpartum. This short-term longitudinal study will use dynamical systems modeling to illuminate temporal
relations between women’s sleep, emotion dysregulation, and SITBs (Aims 1 and 2), as well as how sleep and
emotion dysregulation influence SITBs over time (Aim 3). Dynamical systems modeling is nascent in suicide and
perinatal mental health research, and offers an innovative approach to characterize how constructs interact and
change over time. Moreover, this project’s multiple time-scale design affords a critical opportunity to uncover
how the birth of a child may change the dynamics between these constructs. Given rising rates of suicide among
women of childbearing age as well as devastating consequences of maternal death on children and families, this
project addresses an urgent need to understand the emergence of suicidality across the transition to parenthood.
When the aims of this project are realized, there will be a foundation for future research and interventions
designed to reduce perinatal distress and maternal self-harm-related deaths.

## Key facts

- **NIH application ID:** 10383139
- **Project number:** 5F31MH124275-02
- **Recipient organization:** UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH
- **Principal Investigator:** Parisa Renee Kaliush
- **Activity code:** F31 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $37,850
- **Award type:** 5
- **Project period:** 2020-08-16 → 2022-08-15

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10383139

## Citation

> US National Institutes of Health, RePORTER application 10383139, Daily dynamics of suicide risk, dysregulation, and sleep disruption across the transition to parenthood (5F31MH124275-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10383139. Licensed CC0.

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