# Functional causality in regulating cell morphogenesis

> **NIH NIH R35** · UT SOUTHWESTERN MEDICAL CENTER · 2021 · $200,000

## Abstract

ABSTRACT
 We request funds of $200K with an institutional cost sharing contribution of $150K to assemble a
hyperspectral axially swept light sheet microscope for 3D imaging. The instrument will be tailored to the
requirements of two new experiments that should generate high-resolution image data for analytical scrutiny of
the causal relations between morphogenic signaling pathways and cell shape modulation. The microscope will
support highly sensitive, quasi-simultaneous image acquisition of up to 7 spectrally distinct channels at very low
light exposure and at a spatial resolution of 300 nm in XYZ and second scale temporal resolution.

## Key facts

- **NIH application ID:** 10387909
- **Project number:** 3R35GM136428-02S1
- **Recipient organization:** UT SOUTHWESTERN MEDICAL CENTER
- **Principal Investigator:** Gaudenz Danuser
- **Activity code:** R35 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $200,000
- **Award type:** 3
- **Project period:** 2020-05-01 → 2025-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10387909

## Citation

> US National Institutes of Health, RePORTER application 10387909, Functional causality in regulating cell morphogenesis (3R35GM136428-02S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10387909. Licensed CC0.

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