# Administrative Core

> **NIH NIH P30** · WASHINGTON UNIVERSITY · 2022 · $309,378

## Abstract

Summary – Administrative Core (A)
The long-term goals of the Washington University in Saint Louis (WUSTL) Resource-Based Center for
Musculoskeletal Biology and Medicine (a.k.a., the “Center”) are to advance musculoskeletal research
towards a better understanding of the biological basis of disease, and to develop and test biologically based
interventions. We represent a Research Community of 81 investigators with $66 million in annual funding. A
strength of our Research Community is in the use of animal models. Therefore, the overall objective for the
Center and its Administrative Core is to support the development, implementation and evaluation of animal
models for musculoskeletal biology and medicine. We will pursue this objective through our Leadership
activities and Enrichment Program. The Administrative Core will provide leadership of the Center through a
transparent organizational structure. We will coordinate all Center communications to our Research
Community and the broader WUSTL community. We will participate in outreach activities and partnerships
with other campus centers and programs to represent musculoskeletal research interests. We will provide
guidance and oversight of the Research Cores to ensure that they are accessible, cost-effective and state-
of-the-art. Through regular evaluation of utilization and performance, we will ensure that the Cores have
strong impact locally and nationally. Since 2009, we have supported 343 publications that have been cited
6687 times. We propose a multi-faceted Enrichment Program to sustain and enhance the environment for
musculoskeletal research at WUSTL, and to foster the development of the next generation of
musculoskeletal investigators. Through a Pilot & Feasibility (P&F) Grant Program we will provide seed
funding for meritorious projects that have potential to build to larger grant proposals, and that provide critical
support to Early Stage Investigators or those new to musculoskeletal research. Since its inception, P&F
Program awardees have earned 21 external grant awards on work related to their pilot grants. We will also
provide numerous opportunities for exchange of new ideas and findings, through research and educational
seminars, symposia and networking events. Lastly, we will support rigorous research approaches by
providing expert consulting on the use of mouse genetic models, as well as study design and biostatistics.
In summary, we will provide essential support for our Research Community to develop, implement and
evaluate animal models for musculoskeletal biology and medicine, while fostering development of the next
generation of musculoskeletal investigators.

## Key facts

- **NIH application ID:** 10388080
- **Project number:** 5P30AR074992-04
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** MATTHEW J SILVA
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $309,378
- **Award type:** 5
- **Project period:** 2019-04-15 → 2024-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10388080

## Citation

> US National Institutes of Health, RePORTER application 10388080, Administrative Core (5P30AR074992-04). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10388080. Licensed CC0.

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