# Exposure Core

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2022 · $84,979

## Abstract

PROJECT SUMMARY – Exposure Core 
A robust exposure assessment is key to the success of any environmental epidemiology or toxicology project 
and determining exposure can be complex as people are exposed to multiple compounds through multiple 
exposure pathways. During the initial funding period, the Exposure Core has become a well-known hub on 
campus for seeking advice on the exposure related portion of study design and for developing new and helpful 
methods and facilities to further environmental health research. The Exposure Core has helped connect 
investigators with analytical laboratories that can help further their exposure characterization, assisted 
epidemiologists with robust exposure assessment design, and aided toxicologists to quantify exposures and 
relate them to a relevant benchmark or tissue level. For multi-chemical scenarios, The Core has helped ensure 
that laboratory exposures model real-world human exposure scenarios. The overarching goal of the Exposure 
Core is to provide comprehensive exposure study design and analysis expertise to improve the quality of 
studies that require exposure assessment for epidemiological studies and exposure environments for 
toxicological studies, and hence improve the quality of environmental health research conducted at UC Davis. 
Exposure Core laboratories include expertise in: 1) target and non-target analysis of organic compounds in 
environmental and biological samples, 2) time-integrated or time-window specific exposure concentrations, 3) 
compositional analysis of environmental samples to identify organic functionality via FTIR and mass 
spectrometry and elements and isotopes via XRF and ICPMS analysis, 4) design guidance for animal 
inhalation toxicology studies from a range of air pollutants and sources, 5) resources for helping environmental 
justice communities determine potential exposures, an exposure vivarium for traffic related airborne particles, 
and 5) a portable wildfire measurement system. Core members continue to expand the capabilities of their labs 
to meet these growing needs of center members. The core is increasing our capabilities in helping faculty 
working with community groups to evaluate compounds of concern and develop streamlined methods for 
evaluating community exposures. The Exposure Core has developed a program to provide seed funding to 
investigators for method development to build capabilities. The Exposure Core also provides both subsidies 
and seed funding for sample analysis in the core laboratories for center members. We provide advice on the 
study design through Specific Aims Reviews hosted by the Administrative Core, through Exposure Design 
Reviews for potential pilot applicants, and through meetings with investigators. By providing exposure 
assessment expertise to investigators as part of an integrated core, rather than via independent campus 
laboratories, we will be able to provide a much more robust, appropriate, and custom tailored exposu...

## Key facts

- **NIH application ID:** 10388389
- **Project number:** 5P30ES023513-08
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** Deborah Hall Bennett
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $84,979
- **Award type:** 5
- **Project period:** 2015-05-05 → 2025-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10388389

## Citation

> US National Institutes of Health, RePORTER application 10388389, Exposure Core (5P30ES023513-08). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10388389. Licensed CC0.

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