The Virginia Commonwealth University (VCU) Massey Cancer Center (MCC) created the new Cancer Biology (CB) program in 2020 by merging the former Cancer Cell Signaling and Cancer Molecular Genetics programs. The overreaching goal of this restructuration is to build a robust transdisciplinary scientific environment that enhances collaborative interactions among all MCC members and provide increased opportunities to leverage new scientific concepts with the potential to deliver groundbreaking therapeutic approaches to curb all human malignancies. To achieve these objectives, the CB program created 3 specific aims that encompass the vast majority of research areas being pursued within the MCC catchment area and across Virginia Commonwealth University (VCU) in general.