# Synergy of lipolysis and lipophagy in alcoholic liver disease

> **NIH NIH K99** · MAYO CLINIC ROCHESTER · 2021 · $40,986

## Abstract

Project Summary/Abstract
The purpose and scope of this supplement is to provide additional funds to mitigate disruptions
caused by the COVID19 pandemic on research and training activities related to my parent grant
(K99 AA026877). The parent grant seeks to define new mechanisms of lipid catabolism
affecting alcoholic liver disease (ALD). The research activities during this period will address
Specific Aim 2, which seeks to define a novel, endo-lysosome based mechanism of
microlipophagy that is impacted by alcohol consumption. In addition, this supplement will allow
me to complete my proposed training in the use of animal models of ALD. The results gained
from the proposed research will provide a mechanistic understanding of lipid droplet catabolism
in alcoholic fatty liver. Importantly, these studies will provide published research manuscripts
and preliminary data in support of a future R01 proposal.

## Key facts

- **NIH application ID:** 10392064
- **Project number:** 3K99AA026877-02S1
- **Recipient organization:** MAYO CLINIC ROCHESTER
- **Principal Investigator:** Micah Schott
- **Activity code:** K99 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $40,986
- **Award type:** 3
- **Project period:** 2019-05-20 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10392064

## Citation

> US National Institutes of Health, RePORTER application 10392064, Synergy of lipolysis and lipophagy in alcoholic liver disease (3K99AA026877-02S1). Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/grant/nih/10392064. Licensed CC0.

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