# ADRD Prevention Messaging to Increase Smoking Cessation Attempts in Older Adult Smokers

> **NIH NIH K23** · UNIVERSITY OF WISCONSIN-MADISON · 2022 · $167,323

## Abstract

PROJECT SUMMARY/ABSTRACT
This career development proposal resubmission is designed to provide Adrienne Johnson, PhD, the training
necessary to become an independent investigator in the fields of tobacco dependence, Alzheimer’s disease and
related dementias (ADRD), and dissemination and implementation (D&I) science. Dr. Johnson is trained as a
clinical psychologist and has substantial experience with patient-oriented research in comorbid medical and
psychiatric populations and expertise in smoking cessation within these populations. An expert mentoring team
will guide her in achieving four training objectives: (1) develop a comprehensive understanding of ADRD
etiological factors, prevention literature, and treatment approaches; (2) develop expertise in D&I science and its
application to intervention development and testing; (3) develop expertise in public health marketing and
motivational messaging; and (4) obtain training in larger scale clinical trial methodology. This training, consisting
of formal coursework, guided mentoring, an apprenticeship, and participation in national scientific conferences,
will allow Dr. Johnson to develop and test an intervention designed to help motivate older smokers quitting
smoking. Older adult smokers are at elevated risk for cognitive decline and ADRD development and, unless they
can successfully quit smoking, their prevalence will continue to rise. Unfortunately, older smokers are half as
likely to attempt to quit smoking and less likely to receive evidence-based smoking treatments (EBSTs)
compared to younger adults. Lower cessation efforts in older smokers may be a function of both clinician inaction
and dysfunctional beliefs/motivational deficits of older smokers. The proposed work will develop and test a readily
translatable Stage 1 motivational intervention for smoking cessation in older adults consisting of: (1) a novel
patient-informed motivational message promoting smoking cessation, and (2) clear access routes to EBSTs
within a healthcare setting. The proposed research will use three interrelated aims, occurring consecutively and
building off of findings from the previous aim, to achieve this objective. Aim 1 will identify the most promising
message content in terms of smoking cessation motivation and efficacy of and access to EBSTs in a healthcare
setting. Aim 2 will evaluate promising motivational intervention packages using survey methodology. Finally, Aim
3 will examine the feasibility and preliminary effectiveness of a novel comprehensive motivational intervention to
increase motivation to quit, quit attempts, and use of EBSTs for older adult smokers in a real-world clinical setting.
Dr. Johnson will apply a widely used model of health behavior change (Health Belief Model) to guide treatment
development and use a well validated D&I science framework (RE-AIM) to ensure she is building for translation.
Results will inform a future R01 application aimed at implementing and evaluating this interventio...

## Key facts

- **NIH application ID:** 10398196
- **Project number:** 5K23AG067929-02
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **Principal Investigator:** Adrienne L. Johnson
- **Activity code:** K23 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $167,323
- **Award type:** 5
- **Project period:** 2021-05-01 → 2026-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10398196

## Citation

> US National Institutes of Health, RePORTER application 10398196, ADRD Prevention Messaging to Increase Smoking Cessation Attempts in Older Adult Smokers (5K23AG067929-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10398196. Licensed CC0.

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