# Pelvic Floor Disorders Network 2015

> **NIH NIH UG1** · UT SOUTHWESTERN MEDICAL CENTER · 2021 · $273,785

## Abstract

Pelvic Floor Disorders Network Cycle IV – Administrative Supplement – UT Southwestern
PROJECT SUMMARY / ABSTRACT
 Our primary goal remains to actively engage in the Pelvic Floor Disorders Network (PFDN) through
efficient patient recruitment, participation, and retention of a racially and ethnically diverse patient population in
all studies examining pelvic floor disorders (PFDs) in women. Our second goal is to bring innovative research
proposals to this Network with emphasis on translational aims that explore the pathophysiology and prevention
of PFDs in well-defined clinical study populations. To accomplish these aims, we describe the qualifications and
experience of the Female Pelvic Medicine and Reconstructive Surgery (FPMRS) faculty and research teams at
the University of Texas Southwestern Medical Center and Parkland Hospital, the facilities and patient population
available to carry out clinical protocols, and our state-of-the-art scientific approaches to the study of PFDs. The
clinical research team described in this application actively participated in Cycles II and IV of the PFDN and
achieved robust recruitment and retention for each PFDN clinical trial. Our clinical and research clinics serve
both medically indigent patients (Parkland Hospital) and private, insured patients (university practice). These
clinics provide a diverse patient population which allowed us to be the leading recruiter of Latina women in the
PFDN (Cycle II). We have been active in all other aspects of the PFDN including concept proposal, committee
participation, and manuscript preparation. Unique to our research site/ team is the Biorepository for the PFDN,
which has remained housed at UT Southwestern in Cycles II-IV and has become integral to other translational
research endeavors. Further, the scientific resources and infrastructure within our Ob/Gyn department are
centrally focused on the role of genomics, epigenetics and gene regulation in various aspects of women’s health.
The FPMRS physicians at UT Southwestern remain dedicated to rigorous controlled trials intended to objectively
evaluate principles of non-surgical and surgical care consistent with the mission of the PFDN. With a growing,
diverse clinical patient population, a committed and seasoned research team with a pedigree of successful
internal and external collaborations, and the resources and expertise to champion additional translational PFD
research, UT Southwestern is ready and energized to continue all PFDN activities through the “bridge year”
following Cycle IV.

## Key facts

- **NIH application ID:** 10402187
- **Project number:** 3UG1HD054241-15S1
- **Recipient organization:** UT SOUTHWESTERN MEDICAL CENTER
- **Principal Investigator:** David Dwight Rahn
- **Activity code:** UG1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $273,785
- **Award type:** 3
- **Project period:** 2006-09-12 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10402187

## Citation

> US National Institutes of Health, RePORTER application 10402187, Pelvic Floor Disorders Network 2015 (3UG1HD054241-15S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10402187. Licensed CC0.

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