# Program for AIDS Clinical Research Training (PACRT)

> **NIH NIH T32** · MASSACHUSETTS GENERAL HOSPITAL · 2022 · $617,250

## Abstract

Project Summary
Over the past 40 years, dramatic advances in the understanding of HIV infection and its therapy have
transformed HIV into a highly treatable, chronic disease. Along with this evolution, critical questions have
arisen about how basic research and clinical trials can best be linked to clinical epidemiology and outcomes
research, both in the U.S. and internationally. The goal of the Program for AIDS Clinical Research Training
(PACRT) — which has successfully trained multiple generations of leading HIV clinical investigators for the
past 30 years — is to provide training in quantitative research methodologies with a focus on HIV clinical
research to pre-doctoral PhD students and physician investigators at the most formative stages of their
careers. This training has prepared both groups to conduct clinical research of the highest quality and of direct
relevance to the prevention and treatment of HIV infection. These young investigators have made important
and substantive contributions to the scientific literature and to HIV clinical care and policy, and a large majority
have developed into successful independent investigators. In the next grant cycle, the PACRT trainees will
receive two years of research training under the close supervision and mentorship of one or more of the 14
diverse and experienced program faculty members. Trainees will receive didactic training at the Harvard T.H.
Chan School of Public Health or other Harvard University sites. Primary performance sites for the five post-
doctoral fellows will be the Massachusetts General Hospital, Beth Israel Deaconess Medical Center, Brigham
and Women's Hospital, Boston Children’s Hospital, and Harvard Medical School. The primary site for the two
pre-doctoral fellows will be the Harvard T.H. Chan School of Public Health.
This program has three specific aims for its trainees:
 1) To acquire a sufficient body of knowledge of quantitative methods to conduct independent research
 in: clinical epidemiology, outcomes research, implementation science, cost-effectiveness analysis,
 and/or clinical trials in HIV.
 2) To foster the creation of important scientific contributions with the close and longitudinal mentorship
 of program faculty.
 3) To develop a primary research focus and broad understanding of the various aspects of HIV disease
 for novel interdisciplinary investigation, leading to a successful career focused on HIV research.

## Key facts

- **NIH application ID:** 10403057
- **Project number:** 2T32AI007433-31
- **Recipient organization:** MASSACHUSETTS GENERAL HOSPITAL
- **Principal Investigator:** Kenneth Alan Freedberg
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $617,250
- **Award type:** 2
- **Project period:** 1992-09-30 → 2027-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10403057

## Citation

> US National Institutes of Health, RePORTER application 10403057, Program for AIDS Clinical Research Training (PACRT) (2T32AI007433-31). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10403057. Licensed CC0.

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