# 5/21 ABCD-USA Consortium: Research Project Site at UC San Diego

> **NIH NIH U01** · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2021 · $131,570

## Abstract

Adolescent Brain Cognitive Development (ABCD) is the largest long-term study of brain
development and child health in the United States. The ABCD Research Consortium consists of
21 research sites across the country, a Coordinating Center, and a Data Analysis and
Informatics Resource Center. In its first five years, under RFA-DA-15-015, ABCD enrolled a
diverse sample of 11,878 9-10 year-olds from across the consortium, and will track their
biological and behavioral development through adolescence into young adulthood. All
participants received a comprehensive baseline assessment, including state-of-the-art brain
imaging, neuropsychological testing, bioassays, careful assessment of substance use, mental
health, physical health, and culture and environment. A similar detailed assessment recurs
every 2 years. Interim in-person annual interviews and mid-year telephone or mobile app
assessments provide refined temporal resolution of developmental changes and life events that
occur over time with minimal burden to participating youth and parents. Intensive efforts are
made to keep the vast majority of participants involved with the study through adolescence and
beyond, and retention rates thus far are very high. Neuroimaging has expanded our
understanding of brain development from childhood into adulthood. Using this and other cutting-
edge technologies, ABCD can determine how different kinds of youth experiences (such as
sports, school involvement, extracurricular activities, videogames, social media, unhealthy sleep
patterns, and vaping) interact with each other and with a child's changing biology to affect brain
development and social, behavioral, academic, health, and other outcomes. Data, securely and
privately shared with the scientific community, will enable investigators to: (1) describe individual
developmental pathways in terms of neural, cognitive, emotional, and academic functioning, and
influencing factors; (2) develop national standards of healthy brain development; (3) investigate
the roles and interaction of genes and the environment on development; (4) examine how
physical activity, sleep, screen time, sports injuries (including traumatic brain injuries), and other
experiences influence brain development; (5) determine and replicate factors that influence
mental health from childhood to young adulthood; (6) characterize relationships between mental
health and substance use; and (7) specify how use of substances such as cannabis, alcohol,
tobacco, and caffeine affects developmental outcomes, and how neural, cognitive, emotional,
and environmental factors influence the risk for adolescent substance use.

## Key facts

- **NIH application ID:** 10403399
- **Project number:** 3U01DA041089-07S1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN DIEGO
- **Principal Investigator:** Joanna Jacobus
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $131,570
- **Award type:** 3
- **Project period:** 2021-09-15 → 2023-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10403399

## Citation

> US National Institutes of Health, RePORTER application 10403399, 5/21 ABCD-USA Consortium: Research Project Site at UC San Diego (3U01DA041089-07S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10403399. Licensed CC0.

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