# Structure, function, and pharmacology of neuronal membrane transport proteins

> **NIH NIH R35** · DUKE UNIVERSITY · 2021 · $28,175

## Abstract

Project Summary
Membrane transport proteins are responsible for the passage of key molecules and the transfer of
information across cell membranes, which are events central to many important neurobiological
processes. They are designed to selectively recognize a variety of substrates of differing sizes and
physicochemical properties for cellular transport. My overarching research goals are to understand
the design principles of neuronal membrane transport proteins that are involved in pain and/or itch
sensation and transmission, to develop pharmacological tools to modulate their function, and to apply
the information gained from this research to exploit their therapeutic potential using a multidisciplinary
approach including structural biology, electrophysiology, and pharmacology.

## Key facts

- **NIH application ID:** 10403716
- **Project number:** 3R35NS097241-05S1
- **Recipient organization:** DUKE UNIVERSITY
- **Principal Investigator:** Seok-Yong Lee
- **Activity code:** R35 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $28,175
- **Award type:** 3
- **Project period:** 2021-06-01 → 2023-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10403716

## Citation

> US National Institutes of Health, RePORTER application 10403716, Structure, function, and pharmacology of neuronal membrane transport proteins (3R35NS097241-05S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10403716. Licensed CC0.

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