# Dementia Determinants in Caribbean and U.S. Hispanics

> **NIH NIH R01** · UNIVERSITY OF CALIFORNIA BERKELEY · 2021 · $147,794

## Abstract

PROJECT SUMMARY/ABSTRACT
“Dementia Determinants in Caribbean and U.S. Hispanic Populations”
This proposal in response to PAR-17-470 will significantly expand knowledge regarding
dementia determinants and consequences in Caribbean-origin populations. We build on the
10/66 Dementia Research Group’s internationally harmonized surveys in capital city metro
areas of Puerto Rico, Dominican Republic, and Cuba; these three islands/countries are the
origin of the vast majority of Caribbean immigrants to the U.S. We will compare these data
with the U.S. Health and Retirement Study, and particularly its Healthy Cognitive Aging Project
(HCAP) sub-study which was designed for such international comparisons of dementia. 10/66
data indicate a remarkably high dementia prevalence of 10-12% among adults ages 65+ in these
three Caribbean sites, whose similar histories but richly varying societal structures over the past
century offer great promise for better understanding dementia in Caribbean-origin immigrant
populations. Our international collaborative team will focus on three specific aims: (1) Collect
new baseline survey data in non-metro Puerto Rico and Dominican Republic that parallel
existing 10/66 samples from capital city areas, to better capture the variation in lifecourse
exposures in these sending islands/countries. (2) Analyze dementia relationships with
hypothesized lifecourse socioeconomic determinants across contexts, exploiting comparisons
across vastly heterogeneous life circumstances to both understand drivers of dementia
prevalence and to simulate how prevalence could plausibly be different under altered social
circumstances. (3) Analyze the comparative societal costs of dementia (including both formal
and informal care) to simulate how these costs could plausibly be different under altered
societal arrangements.

## Key facts

- **NIH application ID:** 10404335
- **Project number:** 3R01AG064778-03S1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA BERKELEY
- **Principal Investigator:** William H Dow
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $147,794
- **Award type:** 3
- **Project period:** 2019-08-01 → 2024-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10404335

## Citation

> US National Institutes of Health, RePORTER application 10404335, Dementia Determinants in Caribbean and U.S. Hispanics (3R01AG064778-03S1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10404335. Licensed CC0.

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