# Institutional Career Development Core

> **NIH NIH KL2** · UNIVERSITY OF COLORADO DENVER · 2022 · $775,990

## Abstract

PROJECT SUMMARY/ABSTRACT
Recent publications emphasize a shortfall in the number of investigators and scientists entering the clinical and
translational research (CTR) pipeline. In response to the crisis, NCATS KL2 career development programs play
an increasingly important role in preparing the next generation of clinical-translational scientists to be capable
and resilient in the face of changes in health care, research funding and academic medicine. Our overall goal is
to build upon the success of our CCTSI KL2 program and to provide in the next grant cycle a comprehensive
Institutional Career Development Core KL2 training program, for 5 KL2 junior investigator scholar slots for 3
years each at 75% effort, that will foster outstanding and efficient clinical-translational research education,
promote clinical-translational science competence and excellence, and augment the impact of research
performed by KL2 scholars. To achieve our goals, we propose 3 Specific Aims that are congruent with our
conceptual model of CTR persistence developed by our CCTSI colleagues: Aim 1: Optimize the provision of
individualized competency-based training in translational research methodologies, clinical trials, and data
informatics, along with ethical, regulatory and Good Clinical Practice principles. Aim 2: Prepare KL2 scholars to
thrive in the new collaborative research environment by fostering skill development in entrepreneurship, team-
based science and mentorship. Aim 3: Assure that KL2 scholars develop and submit competitive grant
applications to transition to independent investigators. These specific aims will be achieved through the use of
individualized career development plans to facilitate KL2 scholar oversight and guidance by KL2 program
leadership in completing milestones and goals. KL2 scholars along with their mentors, as a dyad, will complete
the yearlong CO-Mentor program to solidify effective mentoring relationships. Immersion into CTR will involve
meaningful CTR research experiences with the scholar's mentors to support the transition to independence.
Innovative experiences, in the form of externships with community organizations and businesses/industry will be
provided. Career development initiatives will be offered in team science, entrepreneurship, data informatics and
translation through dissemination and implementation. All scholars will complete training in the responsible
conduct of research and Good Clinical Practice. KL2 program leadership will be engaged in several activities to
increase diversity including partnering with the School of Medicine's Office of Diversity and Inclusion and the
University's Office of Inclusion and Outreach. All KL2 scholars will participate in the KL2 Curriculum, and many
of the programs will be available to other junior faculty with NIH K or equivalent awards, enhancing CTR research
training and collaboration across the CCTSI and the University. Key outcomes for the KL2 program will be the
success rate of K...

## Key facts

- **NIH application ID:** 10406153
- **Project number:** 5KL2TR002534-05
- **Recipient organization:** UNIVERSITY OF COLORADO DENVER
- **Principal Investigator:** ELLEN L BURNHAM
- **Activity code:** KL2 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $775,990
- **Award type:** 5
- **Project period:** 2018-05-01 → 2024-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10406153

## Citation

> US National Institutes of Health, RePORTER application 10406153, Institutional Career Development Core (5KL2TR002534-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10406153. Licensed CC0.

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