# Cancer Center Support Grant

> **NIH NIH P30** · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2021 · $150,000

## Abstract

Project Summary
Young Adult (YA) survivors of childhood cancer (ages 18-39), have unique medical and psychosocial needs that
may differ from older survivors, with reproductive health being a paramount concern. Reproductive health for YA
survivors extends beyond infertility and fertility preservation to include other interrelated components:
contraception for pregnancy and sexually transmitted infection prevention; HPV vaccine; and assessment of
sexual health and functioning and the promotion of quality of life. NCCN (1.2021) survivorship guidelines
recommend addressing late effect related to: ovarian function; estradiol levels; treatment for vasomotor
symptoms and vaginal dryness; androgen depravation symptoms; sexual function; HPV vaccine
recommendation; sexual health and function; and fertility related concerns. However, the extent to which these
issues are addressed and documented is not well understood at NYU Perlmutter Cancer Center (PCC) and
gauging our rates will allow us to develop future interventions for improvement. Coupled with individual factors
that may hinder survivorship reproductive health counseling are institutional/practice level barriers that impede
the timely offer of counsel, service or referrals for care. Several studies have concluded that lack of dedicated
models of care to address reproductive health within the institution, clinician lack of time or training, and absence
of a policy requiring such discussions all negatively impact quality reproductive care for AYA. Additionally, the
examination of organizational factors such as policies and pathways may shed light on barriers and facilitators.
PCC, is uniquely qualified to conduct this study. Our EPIC data review identified over 1300 patients currently
receiving care at PCC diagnosed prior to age 18 and now aged 18-40. Thus, we have a large database of YA
cancer survivors to identify documentation of reproductive health issues as per NCCN guidelines. The goals of
this study are to conduct a retrospective chart review of YA survivors to identify documentation of counsel or
referral for reproductive health concerns (sexual health/sexual dysfunction; HPV vaccine recommendation;
contraception; and fertility related concerns) and examine if presence or absence of documentation is associated
with patients’ pediatric cancer diagnosis, stage, treatment and status, parity, gender/identity, sexual orientation
or payor status and examine if these patient characteristics, alone or in combination, are associated with the
odds of documentation of attending to reproductive health issues. Additionally, we will conduct a policy and
pathway analysis to identify if any PCC policies and or pathways support or address reproductive health using
the Livestrong Recommended Practices for AYA. An outstanding team of experts in YA reproductive health,
pediatric & YA cancer and survivorship, medical records, policy analysis and behavioral statistics will conduct
this study and results will have si...

## Key facts

- **NIH application ID:** 10406414
- **Project number:** 3P30CA016087-40S1
- **Recipient organization:** NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- **Principal Investigator:** BENJAMIN G. NEEL
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $150,000
- **Award type:** 3
- **Project period:** 1997-12-01 → 2024-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10406414

## Citation

> US National Institutes of Health, RePORTER application 10406414, Cancer Center Support Grant (3P30CA016087-40S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10406414. Licensed CC0.

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