# Aligning the Alliance of Genome Resources with FAIR and TRUST principles

> **NIH NIH U24** · CALIFORNIA INSTITUTE OF TECHNOLOGY · 2021 · $193,913

## Abstract

PROJECT SUMMARY
The Alliance of Genome Resources (the Alliance) is a “knowledge commons” for expertly curated genomic
data and annotations by model organism databases (MODs) and the Gene Ontology Consortium (GOC). Our
mission is to facilitate the use of model organisms to understand human biology and disease. The Alliance is
organized as two interconnected functional units: Alliance Central and Alliance Knowledge Centers. Alliance
Central is responsible for development and maintenance of the software platform and shared modular
infrastructure and for the coordination of data harmonization activities across the Knowledge Centers. Alliance
Knowledge Centers such as the MODs and the GOC are responsible for expert curation and for submission of
data to Alliance Central using common data formats. Knowledge Centers also are responsible for organism-
specific user support activities, resources, and user access to data not yet supported by Alliance Central. The
data management principles of the Alliance align well with the principles represented by FAIR principles
(Findability, Accessibility, Interoperability, Reusability) and operational approaches reflected in the TRUST
principles (Transparency, Responsibility, User focus, Sustainability and Technology). The focus for the
administrative supplement in response to NOT-OD-21-089, includes the following aims: (1) address areas of
improvement documented for the Alliance of Genome Resources (Alliance) in a FAIRShake assessment
conducted under the auspices of the NIH Common Fund Data Ecosystem Project, (2) complete the Alliance's
application to obtain Core Trust Seal certification, and (3) update information about the data and annotation
licensing terms at the Alliance hosted on the (Re)usable Data Project (RDP). We will also participate in the
workshops and meetings described in NOT-OD-21-089 which will allow the Alliance to compare the
metrics/indicators we use to evaluate the impact of our resource to those of other relevant data resources and
to adapt our metrics as needed to conform to new community standards or trends. The outcomes of the
proposed work align well with the intent of NOT-OD-21-089 to increase the compliance of community data
resources with FAIR and TRUST principles that are foundational to a modern data science ecosystem for the
biomedical research community.

## Key facts

- **NIH application ID:** 10407901
- **Project number:** 3U24HG010859-03S1
- **Recipient organization:** CALIFORNIA INSTITUTE OF TECHNOLOGY
- **Principal Investigator:** CAROL J BULT
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $193,913
- **Award type:** 3
- **Project period:** 2019-09-18 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10407901

## Citation

> US National Institutes of Health, RePORTER application 10407901, Aligning the Alliance of Genome Resources with FAIR and TRUST principles (3U24HG010859-03S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10407901. Licensed CC0.

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