# HPV Vaccination EBI Adaptation in Collaboration with NPAIHB's NW Tribal Comprehensive Cancer and Knight Cancer Institute's Community Outreach & Engagement programs

> **NIH NIH P30** · OREGON HEALTH & SCIENCE UNIVERSITY · 2021 · $150,000

## Abstract

Project Summary/Abstract
OHSU's Knight Cancer Institute Community Outreach and Engagement program and the NPAIHB's Northwest
Tribal Comprehensive Cancer program (NTCCP) will collaboratively unite in the ongoing national, regional and
tribal goal of improving Human Papillomavirus (HPV) vaccination uptake in Oregon tribes. The Knight's
catchment area, the state of Oregon, has a large geographic footprint with communities ranging from densely
populated Portland, to frontier regions of farmers, ranchers and agricultural workers along the Eastern border.
Two-thirds of our 36 counties are categorized as “non-metropolitan” (Rural-Urban Continuum codes (RUCC) 4-
9), resulting in over a quarter of the population residing in rural or frontier areas with limited access to health
care and prevention strategies. Additionally, Oregon is home to nine federally recognized tribes, most of which
are located in rural regions. The Northwest Portland Area Indian Health Board (NPAIHB) is a regional non-
profit organization that represents and serves the 43-federally recognized tribes of the Pacific Northwest as
well as houses the NTCCP.
Dr. Amanda Bruegl, a citizen of the Oneida Nation and descendant of the Stockbridge-Munsee Band of
Mohican Indians and a gynecologic oncologist will be leading this project from KCI. A publication by Dr. Bruegl
and the NPAIHB's Tribal Epidemiology Center shows that the disparities suffered by AI/AN women have
persisted over time with 1.5X incidence and nearly 2X the mortality rate, as well as nearly 3X the mortality rate
in older age groups, when compared to their NHW counterparts.2 Increasing awareness among AI/ANs of the
relationship between HPV and cervical cancer is an established objective within NTCCP's Twenty-Year
Cancer plan. Most recently available data in the Pacific Northwest show that up-to-date HPV vaccination rates
in Tribal youth are higher than other rural youth. In 2020, 67.5% of AI/AN adolescents had completed their
HPV immunization series, compared to 56.1% of White adolescents. However, these rates still remain below
the Healthy People 2020 target of 80%. Overall up-to-date rates vary widely between clinics, with the highest
up-to-date clinic rates at 80% and the clinic with the lowest rates at 32%, as of July 2020. This grant proposes
leveraging the partnership between Knight COE and the NTCCP to 1) assure updated evidence-based
guidelines are included in the Indian Health Service HPV Best Practices Guide, 2) increase provider
knowledge and comfort with HPV vaccination as a cancer prevention tool, 3) increase provider knowledge and
comfort with updated cervical cancer screening guidelines, 4) create culturally tailored HPV vaccination
materials and media and 5) evaluate and disseminate all materials and trainings throughout Oregon tribal
regions as well as within KCI clinics in which tribal youth receive care.

## Key facts

- **NIH application ID:** 10409143
- **Project number:** 3P30CA069533-23S4
- **Recipient organization:** OREGON HEALTH & SCIENCE UNIVERSITY
- **Principal Investigator:** BRIAN J DRUKER
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $150,000
- **Award type:** 3
- **Project period:** 1997-08-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10409143

## Citation

> US National Institutes of Health, RePORTER application 10409143, HPV Vaccination EBI Adaptation in Collaboration with NPAIHB's NW Tribal Comprehensive Cancer and Knight Cancer Institute's Community Outreach & Engagement programs (3P30CA069533-23S4). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10409143. Licensed CC0.

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