# Nathan Shock Center-San Antonio, Aperio VERSA 8 scanning microscope

> **NIH NIH P30** · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · 2021 · $84,849

## Abstract

The purpose of this administrative supplement is to request funds to purchase a scanning microscope
that will further improve the Core service provided by the Pathology Core of the Nathan Shock Center
(NSC) in San Antonio. The Pathology core has been part of the NSC for about 26 years to a) provide
pathology services to local, national, and international investigators for the characterization of animal
models (mice, rats, naked mole-rats, and non-human primates) of aging, and b) examine the effects of
various interventions (dietary, genetic, and pharmacological) on age-related histopathological changes.
The service of the Pathology Core is available to and has been used by investigators from the other cores
of the San Antonio NSC, the Intervention Testing Program, San Antonio, Pepper Center, other
departments at UT Health, and at other academic institutions in the United States. One of the strengths
of the SA Shock Center is our long record of accomplishment in detailed pathological analyses of rodent
colonies for investigators focused on aging research, in which we capitalize on the expertise of Drs. Ikeno
and Hubbard in the conduct of aging-focused histopathological analyses. The Pathology Core provides
investigators with pathology services in aging animal models (mice, rats, naked mole-rats, and non-
human primates) and makes the resulting data widely available to the scientific community. Historically,
the biogerontology field has been hampered by a lack of well-documented pathology data; without it,
survival data provide only limited information about aging. Furthermore, many pathological processes are
modulated by nutritional and other putative aging-modulating interventions (e.g., genetic and
pharmacological). A major reason for lack of pathology data in many aging studies has been very limited
access to pathologists with expertise in aging research. The SA Shock Center has a long record of
accomplishments in detailed pathological analyses of rodent colonies for investigators focused on aging
research conducted by Drs. Ikeno and Hubbard. In addition to the pathology services in aging animal
models (mice, rats, naked mole-rats, and non-human primates), the Pathology Core has been developing
a comprehensive archive of histopathological data and images of histopathology slides as a resource for:
a) trend analyses by investigators; and b) basic pathological information for new studies. Furthermore,
the Pathology Core has developed a tissue archive containing paraffin and frozen blocks, and frozen
tissues, with which we provide additional services to make tissue array slides and unstained paraffin or
frozen sections, perform histological staining (including special staining), and perform laser capture
microdissection.
 Recently, the Pathology Core has received numerous inquiries to provide “slide auto-scanning”
service by the scanning microscope because of the emerging interest and demand to perform “Spatial
Transcriptomics.” This cutting-edge ...

## Key facts

- **NIH application ID:** 10409932
- **Project number:** 3P30AG013319-27S1
- **Recipient organization:** UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
- **Principal Investigator:** PETER J HORNSBY
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $84,849
- **Award type:** 3
- **Project period:** 1997-07-15 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10409932

## Citation

> US National Institutes of Health, RePORTER application 10409932, Nathan Shock Center-San Antonio, Aperio VERSA 8 scanning microscope (3P30AG013319-27S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10409932. Licensed CC0.

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