# UT Southwestern Center for Translational Medicine

> **NIH NIH UL1** · UT SOUTHWESTERN MEDICAL CENTER · 2022 · $7,940,539

## Abstract

Contact PD/PI: Toto, Robert D
OVERALL: PROJECT SUMMARY/ABSTRACT
The Center for Translational Medicine (CTM) at UT Southwestern is a collaboration among 7 academic
institutions, 5 health care systems, 6 teaching hospitals and the North Texas community. Our mission is
to
improve health in local and global communities through innovation and education.
Over the past two funding
cycles, our CTSA catalyzed innovation and transformed the culture and landscape of our program Hub. We
have trained >1,000 members of the translational workforce, co-led the formation of the Accrual to Clinical
Trials CTSA network and established new translational technologies, methods, and processes critical to the
translational process at every level. We engaged our local communities early on in the design and conduct of
clinical research. We also formed new collaborative research services and education and training programs
designed to address the top health challenges of our community and the nation. Through these efforts, the
CTM has generated considerable momentum toward advancing translational science propelled by a highly
collaborative environment that is hard-wired for Team Science and Community Engagement.
 Over the next 5 years, we will optimize the organization of our CTSA Hub for more efficient translation
of biomedical discoveries into interventions that will ultimately result in the improved health of both our local
populations and, in collaboration with the CTSA Network, the broader U.S. population. We will discover,
develop, demonstrate, and disseminate new informatics and artificial intelligence solutions to challenging
problems in translation at all levels. In collaboration with Hub partners and relevant national CTSA networks,
we propose to develop new methods and processes to further the integration of research into practice at the
point of care. Building on our success, we are now poised to achieve the five key objectives of the CTSA
Program and the Center for Translational Medicine with the following Specific Aims:
Aim 1. Produce a well-trained, highly skilled, diverse Translational Workforce.
Aim 2. Inculcate Community Engagement and Team Science.
Aim 3. Integrate diverse populations across the lifespan into clinical and translational research.
Aim 4. Promote innovation and new scientific Methods and Processes.
Aim 5. Develop innovative Informatics solutions to overcome translational roadblocks.
Aim 6. Increase Workforce Heterogeneity.
Impact: With our highly-integrated dynamic research and training environment in place, our Hub will have a
powerful and sustained impact on the field of translational science. We will make a major leap forward in the
scope, efficiency, and quality of clinical and translational research for the benefit of our Hub and the national
consortium. We will collaborate with the Center for Leading Innovation and Collaboration, the Trial Innovation
Network, and the Center for Data to Health to bridge the gap between scientific disco...

## Key facts

- **NIH application ID:** 10412141
- **Project number:** 5UL1TR003163-02
- **Recipient organization:** UT SOUTHWESTERN MEDICAL CENTER
- **Principal Investigator:** ROBERT Daniel TOTO
- **Activity code:** UL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $7,940,539
- **Award type:** 5
- **Project period:** 2021-05-26 → 2026-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10412141

## Citation

> US National Institutes of Health, RePORTER application 10412141, UT Southwestern Center for Translational Medicine (5UL1TR003163-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10412141. Licensed CC0.

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