# Research Education Core

> **NIH NIH P30** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2022 · $108,000

## Abstract

RESEARCH EDUCATION COMPONENT PROJECT SUMMARY/ABSTRACT 
 In Alzheimer’s Disease and Related Dementias (ADRD), a rapidly developing field has gained 
comprehensive insights into a host of likely complementary disease mechanisms, shedding light on relevant 
genetic and environmental factors, a continuum of neuropathological abnormalities, biomarkers that represent 
the earliest stages of disease, and an array of clinical presentations. Yet, large gaps in knowledge remain 
regarding disease modeling, genetics and pathophysiology, and of course, treatment. The Columbia University 
(CU) Research Education Component (REC) will be a comprehensive training program to effectively and 
efficiently develop the next generation of ADRD leaders poised to make breakthroughs in ADRD research 
through both established and novel research methods. The CU REC Training Program will provide training for 
researchers comprising two distinct groups: a) those entering ADRD research through conventional training 
paths (e.g., neurologists, neuropsychologists, basic and translational researchers) with great promise to 
contribute to the field in the near term, and b) researchers from non-conventional paths (e.g., 
bioinformatics/data science, engineering, public health, and allied health) who have demonstrated unique and 
accomplished research skills, which if reoriented to ADRD, could make novel and important impacts on ADRD 
research. The REC Training Program enhances primary aims of the CU ADRC: to enable and enhance 
ongoing research efforts in ADRD at CU, and support a diverse group of ADRD researchers making these 
discoveries. The CU REC Training Program provides a structured framework that promising junior researchers, 
identified through our vast institutional research infrastructure, can leverage to establish successful careers in 
ADRD. With ongoing, multidisciplinary mentorship tied to a structured research project, effectively supported 
junior researchers can independently develop hypotheses, critically appraise related literature, and frame a 
sophisticated approach to an appropriately honed research question. Training will include an individualized 
development plan tailored to each trainee and his or her current and future career steps, enabling a 
foundational understanding from which to launch a successful research career. This program will build upon 
the longstanding practices of the CU ADRC and Department of Neurology, the latter having the highest track 
record of trainees becoming academic neurologists of any institution in the world. In sum, the overarching goal 
of the REC Training Program is to develop the next generation of ADRD researchers by: 1) identifying 3-5 
junior investigators with promise for making significant contributions to the field of ADRD (Aim 1); 2) drawing 
trainees from ADRD fields as well as fields beyond traditional pathways to ADRD research, especially those 
from diverse backgrounds (Aim 2); and 3) providing all trainees wi...

## Key facts

- **NIH application ID:** 10413102
- **Project number:** 5P30AG066462-03
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** STEPHANIE Ann COSENTINO
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $108,000
- **Award type:** 5
- **Project period:** 2020-06-15 → 2025-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10413102

## Citation

> US National Institutes of Health, RePORTER application 10413102, Research Education Core (5P30AG066462-03). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10413102. Licensed CC0.

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