# 1Florida Alzheimer's Disease Research Center Biomarker Core

> **NIH NIH P30** · UNIVERSITY OF FLORIDA · 2022 · $527,058

## Abstract

SUMMARY: Biomarker Core
Alzheimer’s disease (AD) classically develops in the elderly. The classical way to confirm an AD diagnosis is the
presence of amyloid deposition and tau pathology at post-mortem; however in-vivo biomarkers can serve as
proxies of these characteristics and are invaluable in separating healthy aging from AD as well as placing
individuals along the AD continuum. The Biomarker Core works closely with the three Clinical Core sites across
Miami and Gainesville, as well as the Data Core to provide timely access to raw, pre-processed, and post-
processed data. The Aims of this Biomarker Core include: 1) Web-based Neuroimaging Portal for Accessing,
Visualizing, and Sharing Multimodal Imaging Data. 2) Integrating New Imaging and Biofluid Modalities into the
Neuroimaging Portal. 3) Multimodal, Multiclass, and Machine Learning Algorithms of Imaging and Biofluid
Markers. 4) Provide Support for Ongoing and Future R01, U01, REC, K01, K99, T32, and F32 grants across the
network of Florida and non-Florida Projects. There is a rich and expansive group of grants that will be able to
leverage the biomarker datasets acquired within the Clinical Core, including those funded as part of the Research
and Education Core (REC). This core will provide the needed communication, data sharing, analysis support,
and neuroimaging training for research in these projects to proceed. We believe that this study, which would be
one of the largest of its kind, will combine data acquired at the Wien Center for Alzheimer’s Disease and Memory
Disorders, UM Center for Cognitive Neuroscience and Aging, and University of Florida. Access to this new
multimodal dataset in AD and other dementias will provide added statistical meaningfulness in studying dementia
and inclusion of a large number of Hispanics and African Americans, which is much needed given the current
demographics of the popular ADNI database.

## Key facts

- **NIH application ID:** 10413196
- **Project number:** 5P30AG066506-03
- **Recipient organization:** UNIVERSITY OF FLORIDA
- **Principal Investigator:** David E Vaillancourt
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $527,058
- **Award type:** 5
- **Project period:** 2020-06-15 → 2025-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10413196

## Citation

> US National Institutes of Health, RePORTER application 10413196, 1Florida Alzheimer's Disease Research Center Biomarker Core (5P30AG066506-03). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10413196. Licensed CC0.

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