# High-Energy Tunable Nanosecond-Pulsed Laser

> **NIH NIH S10** · CALIFORNIA INSTITUTE OF TECHNOLOGY · 2022 · $121,345

## Abstract

The requested instrument is a high-energy broadly tunable nanosecond-pulsed laser
manufactured by Opotek LLC. This instrument will serve as an excitation source for a wide array
of nanosecond time-resolved transient spectroscopies (luminescence, UV-Visible absorption,
FTIR, resonance Raman) as well as an excitation source for steady-state Raman spectroscopy.
The laser will be housed in the Beckman Institute Laser Resource Center, a facility focused on
providing the Caltech research community with instrumentation and guidance in steady-state
and time-resolved laser spectroscopy, conventional spectroscopy, photophysics, and
photochemistry. A primary focus of the Center is time-resolved spectroscopy for measurements
of chemical and biochemical kinetics, and the elucidation of chemical reaction mechanisms. The
laser will furnish essential support for three NIH-funded research programs of Major Users, as
well as three externally funded and three internally funded research programs of Other Users.
The NIH-funded programs include: studies of radical transfer pathways in iron and copper
oxygenases and oxidases; elucidation of the photochemical mechanisms of copper-based
catalysts involved in (enantioselective) C–N bond formation; mechanistic investigations of
dinitrogen reduction chemistry catalyzed by bioinspired iron model complexes; and
investigations of DNA mediated charge transfer processes in Pseudomonas aeruginosa
biofilms. Other research projects utilizing the instrument will address: mechanistic investigations
of lytic polysaccharide monooxygenase catalysis; photophysical investigations of
arylisocyanide-metal complexes; development of table-top plasma sources for soft to hard x-
rays; time-resolved spectroscopic characterization of photoredox mechanisms; and time-
resolved spectroscopic characterization of bipentacene triplet states generated via singlet
fission.

## Key facts

- **NIH application ID:** 10413649
- **Project number:** 1S10OD032151-01
- **Recipient organization:** CALIFORNIA INSTITUTE OF TECHNOLOGY
- **Principal Investigator:** JAY R WINKLER
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $121,345
- **Award type:** 1
- **Project period:** 2022-06-15 → 2023-06-14

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10413649

## Citation

> US National Institutes of Health, RePORTER application 10413649, High-Energy Tunable Nanosecond-Pulsed Laser (1S10OD032151-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10413649. Licensed CC0.

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