# Nutrition-specific interventions to improve long-term maternal-child health outcomes

> **NIH NIH UG1** · UNIVERSITY OF COLORADO DENVER · 2022 · $606,555

## Abstract

PROJECT SUMMARY
Meeting the Sustainable Development Goals' 2030 targets for maternal and child morbidity and mortality will
require sustained and effective public health interventions for the most vulnerable populations. The broad goal
of this application is to continue to participate in all collaborative activities relevant to the mission of the Global
Network (GN), which aims to develop and test potential sustainable interventions through collaborative, large-
scale, high-impact, multi-site common research protocols. The primary objective of our research unit (RU),
which represents a partnership between the University of Colorado and Guatemala, is to develop and
implement nutrition-specific interventions to mitigate the effects of pre- and post-natal malnutrition and thereby
to improve maternal and infant health outcomes. This objective will be met through the following specific aims:
1) continue to maintain a strong research record and productivity as GN members; 2) continue to foster a
progressively stronger research partnership with our colleagues in Guatemala and other GN sites; and 3)
continue to develop nutrition-specific interventions as GN common protocols. During the past 5-yr cycle, this
RU has built a strong research record, as evidenced by having led two major nutrition-specific common
protocols, including the preconception maternal nutrition intervention trial; having strengthened the research
capacity in Guatemala; participation in the development and implementation of all GN-initiated common
protocols with contribution of a high percentage of cluster/participant numbers to each study; strong
productivity in publications (total of 60 with GN co-authors) that report findings of GN supported trials; and
having successfully obtained major external funding to support common protocol implementation. Major
contributions to the GN by this RU include co-chairing the Protocol Review Sub-committee and the oversight
committee for the ongoing Maternal Newborn Health Registry. Successful mentoring and capacity building for
the RU is evidenced from invitation by NICHD for the Sr. Foreign Investigator to be site lead for a multi-country
observational study of Zika virus exposure during pregnancy. The positive impact of our continued participation
in the GN will be to strengthen the multi-disciplinary capacity of the Global Network by identifying nutrition-
specific interventions to improve maternal and infant health. Such collaborative research will accelerate the
development of evidence-based policies to reduce the global burden of malnutrition and other adverse health
outcomes.

## Key facts

- **NIH application ID:** 10413872
- **Project number:** 5UG1HD076474-10
- **Recipient organization:** UNIVERSITY OF COLORADO DENVER
- **Principal Investigator:** NANCY F KREBS
- **Activity code:** UG1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $606,555
- **Award type:** 5
- **Project period:** 2013-07-05 → 2023-08-06

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10413872

## Citation

> US National Institutes of Health, RePORTER application 10413872, Nutrition-specific interventions to improve long-term maternal-child health outcomes (5UG1HD076474-10). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10413872. Licensed CC0.

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