Project Summary / Abstract This application is a supplement to the parent grant entitled “Acute to Chronic Pain Signatures Program” (A2CPS) (U24 NS112873) for postdoctoral training of Dr. Giovanni Berardi. Giovanni will actively participate in all aspects of this multi-site cohort study including recruitment and retention, data collection and management, clinical site training and quality assurance, data analysis, and research dissemination. He has established training goals that are in line with the A2CPS parent grant which will provide invaluable training that will promote career development towards an early career investigator in clinical pain research. The established training aims will be focused towards developing skills necessary to conduct and coordinate multi-site cohort studies, obtaining new knowledge and skills revolving around generation of an “omics” datasets, advancing understanding in application of statistical methods to analyze large cohort datasets, and further development of research dissemination and grant writing. The addition of Dr. Berardi to the A2CPS program will facilitate completion of the parent grant aims and prepare Giovanni with attributes and skills necessary for a career in human subjects clinical pain research.