# Genome Sequencing Core

> **NIH NIH P30** · UNIVERSITY OF KANSAS LAWRENCE · 2022 · $229,500

## Abstract

PROJECT SUMMARY – CORE B
Next generation sequencing is a central tool in the analysis of signaling pathways important in development and
disease. The Genome Sequencing Core (GSC) was established in Phase 1 of the CMADP to provide
researchers at the University of Kansas and the state of Kansas with next-generation sequencing technologies
as well as expertise in experimental design and analysis of sequence data. Projects in the GSC include whole
genome assembly, genome re-sequencing for identification of mutations important in development and disease,
transcriptome analysis (RNA-seq), variant mapping and genotyping, and identification of transcription factor
interaction sites using chromatin immunoprecipitation combined with DNA sequencing (ChIP seq). The GSC
houses Illumina MiSeq and NextSeq 550 sequencers with dedicated processor and storage space to run the
instruments. To keep the GSC on the cutting edge of technology, a NextSeq 2000 instrument will be installed in
the summer of 2021 to enhance and expand services.
Next generation sequencing is an enabling technology in that it has the power to allow investigators from many
different disciplines to ask new questions in their research areas of interest. The GSC enables genomics
research at the University of Kansas by eliminating the barriers of cost and communication involved with using
off-campus facilities. The GSC has been utilized by a broad user base at the University of Kansas, including
Molecular Biosciences, Ecology and Evolutionary Biology, the Natural History Museum, Engineering, Pharmacy,
and the KU Medical Center. Researchers at other universities in Kansas, including Kansas State University,
Wichita State University, and Fort Hays State University have used the GSC. The GSC works with other IDeA
program projects including the K-INBRE and the CBID COBRE. This broad and diverse user base will be key to
the future sustainability of the GSC after Phase 3 as a University Core Research Laboratory.

## Key facts

- **NIH application ID:** 10414317
- **Project number:** 1P30GM145499-01
- **Recipient organization:** UNIVERSITY OF KANSAS LAWRENCE
- **Principal Investigator:** Erik A Lundquist
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $229,500
- **Award type:** 1
- **Project period:** 2022-07-01 → 2027-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10414317

## Citation

> US National Institutes of Health, RePORTER application 10414317, Genome Sequencing Core (1P30GM145499-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10414317. Licensed CC0.

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