# Genomics, Bioinformatics, and Molecular Imaging Core

> **NIH NIH P30** · TULANE UNIVERSITY OF LOUISIANA · 2022 · $544,912

## Abstract

The objective of the Genomics, Bioinformatics, and Molecular Imaging Core is to support and to enhance the
research productivity of both COBRE and non-COBRE investigators. This is measured by our contributions to
their peer-reviewed publications and grant applications. Our clients utilize our services from the study planning
and design phase through the data analysis and presentation phase. The Core currently provides services for
next-generation sequencing (NGS), DNA Sanger sequencing, genotyping, cell line validation, bioinformatics and
biostatistics support, as well as other equipment and services. In Phase III, we will further enhance our core and
organize its operations under three co-directors who have complementary expertise that encompasses all
aspects of services offered. Because of these enhancements, we added ‘Molecular Imaging’ to our moniker. We
will pursue the following specific aims: (1) Maintain access and services for next-generation sequencing (RNA-
Seq, WES, miRNA-Seq, Ampli-Seq), Sanger DNA sequencing with capillary electrophoresis, real-time PCR
applications, measurements for luciferase assays, DNA and RNA isolation, quantitation and quality control of
DNA and RNA with the Agilent 2100 Bioanalyzer and cell line validation for investigators. (2) Expand the
molecular portfolio of core services and implement new NGS applications by establishing Visium Spatial Gene
Analysis using High-plex Proteomics and Whole Transcriptome Analysis, Chromium Single Cell Gene
Expression and Multiome ATAC + Gene Expression using 10x Genomics and Illumina systems. (3) Continue
biostatistics and bioinformatics support for data generated by the core and outside the core and develop new
bioinformatics pipelines. (4) Expand and maintain sustainability and growth of the Core, by implementing recharge
to all services and increase it over the course of Phase III and identify and deploy other sources of support. Our
enhanced instrumentation and expanded personnel will make this possible, and this will help satiate the ever-
increasing appetite for all of these applications. Our data analytic services will allow our clients to receive data
that is not only clean and valid quantitatively but also has been put through a bioinformatics pipeline that makes
it relevant biologically in broader terms. Both the biostatistics and bioinformatics components of the Core will
contribute to the development of new and better approaches to the handling of the data our investigators
generate.

## Key facts

- **NIH application ID:** 10414532
- **Project number:** 1P30GM145498-01
- **Recipient organization:** TULANE UNIVERSITY OF LOUISIANA
- **Principal Investigator:** Malwina Czarny-Ratajczak
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $544,912
- **Award type:** 1
- **Project period:** 2022-06-01 → 2027-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10414532

## Citation

> US National Institutes of Health, RePORTER application 10414532, Genomics, Bioinformatics, and Molecular Imaging Core (1P30GM145498-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10414532. Licensed CC0.

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