# J: NRSA Training Core

> **NIH NIH TL1** · UNIV OF MASSACHUSETTS MED SCH WORCESTER · 2022 · $392,055

## Abstract

Contact PD/PI: Luzuriaga, Katherine NRSA-Training-001 (003)
PROJECT SUMMARY/ABSTRACT – J. NRSA TRAINING CORE
The TL1 program addresses the NCATS unmet need of a prepared translational research workforce. Since the
first cohort was recruited in 2016, the TL1 program has transformed training in translational research at UMMS
from a fragmented, siloed training model to a collaborative training environment, well integrated with UMCCTS
resources. The TL1 program provides didactic training to develop domain expertise, rigorous research, team
science, and communication skills. The TL1 specific aims are to: 1) Assure core competence in clinical and
translational research for highly qualified pre- and early post-doctoral trainees through the provision of a multi-
faceted, rigorous TL1 program; 2) Facilitate a broad spectrum of clinical and translational research responsive
to unmet health needs; 3) Enable efficiency, quality, effectiveness, and reproducibility in the development of
new products or approaches; and 4) Foster transdisciplinary training and team science in research. To achieve
these aims, we have developed 5 structured Research Pathways in Entrepreneurship and Commercialization,
Data Science, Community Engagement, Implementation Science, and a Generalist Pathway. To assure a di-
verse trainee population with respect to clinical background, disciplinary perspective, and those underrepre-
sented in the biomedical sciences, we recruit from national and local pools of eligible candidates. TL1 trainees
self-assess their competency in clinical and translational research as defined by the national CTSA Consortium
and work with mentoring teams to create an individualized competency-based curriculum providing formal and
informal opportunities to develop research skills. Locally, our Council to Advance Trainees and Scholars leads
efforts to reduce redundancy and to integrate translational learning opportunities across the training ecosystem
at UMMS. Regionally and nationally, our trainees learn to use CTSA tools (e.g., i2b2) and engage with CTSA
collaborators (e.g., shared mentoring, research rotations, retreats). In the next funding period, our TL1 Pro-
gram will share our rigor and reproducibility curriculum for use by the CTSA consortium.
Abbreviations: BERD - Biostatistics, Epidemiology, and Research Design; CATS - Council on Advancing
Scholars; COI - Conflict of Interest; CTRP - Clinical and Translational Research Pathway; CVD – Cardiovascu-
lar; DIG - Diversity Interest Group; FDSP - Faculty Development Scholar Program; GCP - Good Clinical Prac-
tice; GSBS - Graduate School of Biomedical Sciences; GSN - Graduate School of Nursing ; IDP - Individual
Development Plan; IMSD - Initiative for Maximizing Student Development ; MPI - Multiple Principal Investiga-
tor; MSCI - Master of Science in Clinical Investigation; MSTP - Medical Science Training Program; PiPSS -
Projects in Progress Seminars; PQHS - Population and Quantitative Health Sciences; PREP ...

## Key facts

- **NIH application ID:** 10414796
- **Project number:** 5TL1TR001454-07
- **Recipient organization:** UNIV OF MASSACHUSETTS MED SCH WORCESTER
- **Principal Investigator:** Kate L Lapane
- **Activity code:** TL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $392,055
- **Award type:** 5
- **Project period:** 2015-08-14 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10414796

## Citation

> US National Institutes of Health, RePORTER application 10414796, J: NRSA Training Core (5TL1TR001454-07). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10414796. Licensed CC0.

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