# Molecular Basis of Viral Infectivity

> **NIH NIH T32** · HARVARD MEDICAL SCHOOL · 2022 · $484,363

## Abstract

Project Abstract
This training program in mechanisms of viral infection will train 6 predoctoral students and 4 postdoctoral
fellows per year. The goal of this training grant is to provide students who 1) are well trained in the study of
mechanisms of viral replication, 2) can investigate human viruses causing disease, such as the human
immunodeficiency virus and herpes viruses, 3) can investigate new antiviral compounds and vaccines to
prevent or treat viral diseases, 4) can study viruses that are emerging threats to human health, and 5) can use
viruses to probe the cellular and molecular biology of prokaryotic and eukaryotic cells. Nearly all of the
predoctoral applicants will have an undergraduate education in biology or chemistry. All of the predoctoral
trainees will be graduate students in the Program in Virology, an inter-faculty degree-granting program. The
laboratories of the training faculty are located at Harvard Medical School and affiliated hospitals, Harvard
School of Public Health, Dana-Farber Cancer Institute, Children's Hospital, and the Harvard University
Fairchild Laboratory in Cambridge. The Program in Virology students pursue a broad biological program of
study with courses in virology, molecular biology and genetics, biochemistry, cell biology and immunology.
These students will also attend seminars, research meetings, and perform 3 laboratory rotations. Faculty
curriculum advisors will provide guidance for the students throughout their training, and they will choose their
advisors from the Program in Virology faculty. Students will take a preliminary qualifying examination during
their second year, and within 6 months form a dissertation advisory committee to provide advice on the
progress of their research. Upon successful completion and defense of the dissertation, the student will be
awarded a Ph.D. degree in virology. Postdoctoral training takes place in the laboratories of the training faculty.
Consistent with the specialized nature of postdoctoral training, the primary program will be designed by the
faculty advisor. This training program is designed to augment that training by engaging the postdoctoral fellow
in virology program retreats, courses, and seminars. Postdoctoral trainees will form a postdoctoral advisory
committee that will meet at least annually to evaluate research and career paths. Predoctoral and postdoctoral
trainees will participate in a training program in the ethical conduct of science. An active and previously
successful program by the training faculty and Division of Medical Sciences is described for the recruitment of
underrepresented minority trainees.

## Key facts

- **NIH application ID:** 10415068
- **Project number:** 5T32AI007245-39
- **Recipient organization:** HARVARD MEDICAL SCHOOL
- **Principal Investigator:** DAVID M. KNIPE
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $484,363
- **Award type:** 5
- **Project period:** 1983-07-01 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10415068

## Citation

> US National Institutes of Health, RePORTER application 10415068, Molecular Basis of Viral Infectivity (5T32AI007245-39). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10415068. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*