# Center for Advancing Multimorbidity Science: Profiling risk and symptom expression to develop customized therapies for adults with multiple chronic conditions (CAMS)

> **NIH NIH P20** · UNIVERSITY OF IOWA · 2022 · $363,407

## Abstract

The overall mission of the Center for Advancing Multimorbidity Science: Profiling risk and
symptom expression to develop customized therapies for adults with multiple chronic conditions
(CAMS) is to enhance interdisciplinary, biobehavioral research focused on complex multiple chronic
conditions in human adult populations.
Its specific purpose is to provide the infrastructure and resources to new investigators and their
collaborators integrating two subfields: Multimorbidity Science and Symptom Science, characterizing risk
susceptibility and treatment responder profiles using advanced analytic techniques. This will allow
clinicians and scientists to identify persons who are more likely to develop specific conditions/symptoms
as well as those who may respond to customized therapies. The specific aims of this Center are to:
1. Develop a sustainable interdisciplinary biobehavioral research capacity by establishing and
 coordinating an infrastructure and resources that facilitates the integration of Multimorbidity and
 Symptom Science through the development of patient risk and therapy responder profiles.
2. Build thematic science beginning with a reconceptualization of the science of Multiple Chronic
 Conditions (Multimorbidity) to include Symptom Science.
3. Enable research that will develop into new programs of science and independent investigator
 research applications.
The Center includes 61 faculty and builds upon the research strengths of the faculty at the University of
Iowa in symptom science and gerontological nursing (FY2018 research base is $1,118,436 in direct
costs). In addition, it is embedded in a strong supportive interdisciplinary network of investigators and
Centers from other University departments and Colleges. We will leverage exceptional University
resources and complete proposed projects and activities to further the integrated hybrid area of
Multimorbidity and Symptom Science. The Center aligns with three thematic areas of the 2016 NINR
Strategic Plan: Symptom Science, Self-Management, End-of-Life and Palliative Care and supports the
NINR Common Data Element (CDE) initiative.

## Key facts

- **NIH application ID:** 10416002
- **Project number:** 5P20NR018081-05
- **Recipient organization:** UNIVERSITY OF IOWA
- **Principal Investigator:** SUE E GARDNER
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $363,407
- **Award type:** 5
- **Project period:** 2018-08-13 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10416002

## Citation

> US National Institutes of Health, RePORTER application 10416002, Center for Advancing Multimorbidity Science: Profiling risk and symptom expression to develop customized therapies for adults with multiple chronic conditions (CAMS) (5P20NR018081-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10416002. Licensed CC0.

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