# Center for Advancing Multimorbidity Science: Profiling risk and symptom expression to develop customized therapies for adults with multiple chronic conditions (CAMS)

> **NIH NIH P20** · UNIVERSITY OF IOWA · 2022 · $26,749

## Abstract

The Directors of this proposed P20 recognized that innovative, advanced analytical techniques such as
predictive modeling and self organizing maps (SOM) are critical to understanding the complex
relationships associated with adults experiencing multiple chronic conditions. The overall goal of the
Integrative Analytics Core is to serve as a centralized resource for data management and advanced
analytical techniques for clinical research projects for the Center. Through faculty and staff with expertise
in using advanced analytical techniques, the Integrative Analytics Core serves as a resource for
consultation/guidance, data collection, data management and data quality control. Core personnel
support the Pilot PIs at all levels of investigation, beginning with the formulation of specific hypotheses,
reviewing of study designs, and evaluating utility of measurement techniques. Mentoring and guidance
continues with the interpretation, presentation, and publication of results, and fostering development of
the projects into successful R-series grants. The specific aims of the Integrative Analytics Core are:
1. Provide multidisciplinary analytics and biostatistical support needed for research questions and/or
 hypothesis testing and grant proposals.
2. Facilitate the collection, management, dissemination and storage of data for projects.
3. Continue to improve the data analytics infrastructure to better handle large variables of
 observations and outcome (predictor) variables.
4. Create educational programs that address basic machine learning and biostatistical training
 needs for large and complex multimodal clinical research studies.
Given the complexity of the questions being asked in this Center related to individuals with multiple
chronic conditions (MCC), a centralized core for analytics is an essential element to the Center's
success. The Integrative Analytics Core will be a resource for all Center Members, making available
advanced analytics support and biostatistical consultation useful for both planning and executing
projects. Given the current push for collection of big datasets and their re-use, this Core will provide a
valuable data sharing resource. In addition, this Integrative Analytics Core will include support to Pilot PIs
and offer educational programs and outreach to Center Members.

## Key facts

- **NIH application ID:** 10416004
- **Project number:** 5P20NR018081-05
- **Recipient organization:** UNIVERSITY OF IOWA
- **Principal Investigator:** William Street
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $26,749
- **Award type:** 5
- **Project period:** 2018-08-13 → 2024-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10416004

## Citation

> US National Institutes of Health, RePORTER application 10416004, Center for Advancing Multimorbidity Science: Profiling risk and symptom expression to develop customized therapies for adults with multiple chronic conditions (CAMS) (5P20NR018081-05). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10416004. Licensed CC0.

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